HitPredict - High confidence protein-protein interactions

Interactor 1: DNAA (P03004)
Chromosomal replication initiator protein DnaA
Gene: DNAA

Interactor 2: DNAA (P03004)
Chromosomal replication initiator protein DnaA
Gene: DNAA

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.755

Property	Details
Experiments	19833870, 18284581
Identification Methods	cross-linking study, affinity chromatography technology
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	Bac_DnaA~Bac_DnaA, Bac_DnaA~Bac_DnaA_C
Common GO terms	GO:0003677 - DNA binding GO:0003688 - DNA replication origin binding GO:0005524 - ATP binding GO:0005829 - cytosol GO:0005886 - plasma membrane and 16 others more... GO:0006260 - DNA replication GO:0006268 - DNA unwinding involved in DNA replication GO:0006270 - DNA replication initiation GO:0006275 - regulation of DNA replication GO:0009898 - cytoplasmic side of plasma membrane GO:0016887 - ATP hydrolysis activity GO:0030174 - regulation of DNA-templated DNA replication initiation GO:0032297 - negative regulation of DNA-templated DNA replication initiation GO:0032298 - positive regulation of DNA-templated DNA replication initiation GO:0043565 - sequence-specific DNA binding GO:1990103 - DnaA-HU complex GO:1990102 - DnaA-DiaA complex GO:1990078 - replication inhibiting complex GO:1990082 - DnaA-L2 complex GO:1990084 - DnaA-Dps complex GO:1990101 - DnaA-oriC complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1	467
Ec

1	467

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Last updated: 15 Jul 2024