Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1
Interactor 2: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.96 | 1.00 | 0.983 |
The method score is based on:
Property | Details |
---|---|
Experiments | 20348541, 10619402, 17991765, 23403292, 12198596, 33731348, 19117995, 20353944, 12554772, 21182205, 23576398, 23159625, 18474858, unassigned1953, 11265755, 11682626 |
Identification Methods | pull down, affinity chromatography technology, two hybrid, fluorescent resonance energy transfer, x-ray crystallography, tandem affinity purification, cosedimentation through density gradient, transcriptional complementation assay |
Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Hormone_recep~Hormone_recep, Hormone_recep~zf-C4, zf-C4~zf-C4 |
Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0000791 - euchromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific and 75 others more... |
Homologous interactions | 19 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024