Protein: FRA1
Putative Xaa-Pro aminopeptidase FRA1 (EC 3.4.11.9) (Fe repressor of activation 1)

Gene: FRA1
Organism: Saccharomyces cerevisiae S288C
Interactions: 40
UniProt ID: Q07825

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006508 - proteolysis
GO:0046872 - metal ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

393426

HSP82
ATP-dependent molecular chaperone HSP82

3

2

High-throughput

0.633

High

525331

HSP71
Heat shock protein SSA1

3

7

High-throughput

0.633

High

916998

BOL2
BolA-like protein 2

2

0

Small-scale

0.585

High

1045055

TSA2
Peroxiredoxin TSA2

2

1

Small-scale

0.584

High

510863

HSP77
Import motor subunit, mitochondrial

2

1

High-throughput

0.571

High

580160

HSC82
ATP-dependent molecular chaperone HSC82

2

2

High-throughput

0.571

High

819949

SSB2
Ribosome-associated molecular chaperone SSB2

2

8

High-throughput

0.552

High

527828

HSP72
Heat shock protein SSA2

1

7

High-throughput

0.536

High

722304

XPO1
Exportin-1

1

2

High-throughput

0.536

High

783513

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.515

High

441274

KAPA
cAMP-dependent protein kinase type 1

1

3

High-throughput

0.501

High

509740

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

2

High-throughput

0.501

High

865555

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

1

High-throughput

0.501

High

1060331

RUP1
UBA domain-containing protein RUP1

1

0

High-throughput

0.493

High

737957

HOG1
Mitogen-activated protein kinase HOG1

1

1

High-throughput

0.479

High

760629

TSA1
Peroxiredoxin TSA1

1

1

High-throughput

0.479

High

800827

RCK2
Serine/threonine-protein kinase RCK2

1

1

High-throughput

0.479

High

850227

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

1

High-throughput

0.479

High

486332

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.458

High

680110

CDC48
Cell division control protein 48

1

0

High-throughput

0.458

High

748077

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

779910

FRE2
Ferric/cupric reductase transmembrane component 2

1

0

High-throughput

0.458

High

804833

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

0

High-throughput

0.458

High

813779

AIM2
Protein AIM2

1

0

High-throughput

0.458

High

917948

PDK2
[Pyruvate dehydrogenase

1

1

High-throughput

0.457

High

546496

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.445

High

590738

HSP26
Heat shock protein 26

1

1

High-throughput

0.445

High

742525

HSP7F
Heat shock protein homolog SSE1

1

9

High-throughput

0.445

High

752803

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

1060332

HSP42
Heat shock protein 42

1

2

High-throughput

0.445

High

708346

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

748562

SC61A
Protein transport protein SEC61

1

1

High-throughput

0.437

High

1060330

ATG9
Autophagy-related protein 9

1

1

High-throughput

0.437

High

811419

CAJ1
Protein CAJ1

1

0

High-throughput

0.426

High

1035141

UBC7
Ubiquitin-conjugating enzyme E2 7

1

1

High-throughput

0.417

High

823297

JEM1
DnaJ-like chaperone JEM1

1

1

High-throughput

0.407

High

1045173

SIZ1
E3 SUMO-protein ligase SIZ1

2

0

High-throughput

0.313

High

678902

CSM1
Monopolin complex subunit CSM1

1

0

High-throughput

0.269

Low

808755

ATU2
Copper-transporting ATPase

1

0

High-throughput

0.249

Low

1060329

MLH3
DNA mismatch repair protein MLH3

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025