HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 0.60 0.740

The method score is based on:

Property Details
Experiments 27483141, 16037132, 15538384, 20308691, 21182205, 9774640, 21182203
Identification Methods affinity chromatography technology, pull down, cosedimentation through density gradient
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 3 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 595
Hs

1 646
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024