Protein: MET18
DNA repair/transcription protein MET18/MMS19 (Methyl methanesulfonate-sensitivity protein 19)

Gene: MET18
Organism: Saccharomyces cerevisiae S288C
Interactions: 75
UniProt ID: P40469

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006259 - DNA metabolic process
GO:0006281 - DNA repair

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

755895

YHS2
MIP18 family protein YHR122W

11

3

Small-scale

0.755

High

774244

CIAO1
Cytosolic iron-sulfur protein assembly protein 1

8

2

Small-scale

0.743

High

420503

RAD3
General transcription and DNA repair factor IIH helicase subunit XPD

5

4

Small-scale

0.718

High

511573

SSB1
Ribosome-associated molecular chaperone SSB1

2

0

High-throughput

0.576

High

774227

MET18
DNA repair/transcription protein MET18/MMS19

1

1

Small-scale

0.575

High

368125

EF1A
Elongation factor 1-alpha

2

0

High-throughput

0.559

High

554664

HSP26
Heat shock protein 26

2

0

High-throughput

0.559

High

494142

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

705257

HSP78
Heat shock protein 78, mitochondrial

2

0

High-throughput

0.547

High

340691

PGK
Phosphoglycerate kinase

1

1

High-throughput

0.536

High

342040

ATPB
ATP synthase subunit beta, mitochondrial

1

1

High-throughput

0.536

High

340160

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.513

High

425627

KAPR
cAMP-dependent protein kinase regulatory subunit

1

0

High-throughput

0.513

High

429713

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

0

High-throughput

0.513

High

454356

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.513

High

604268

MDHC
Malate dehydrogenase, cytoplasmic

1

0

High-throughput

0.513

High

691812

EI2BB
Translation initiation factor eIF2B subunit beta

1

0

High-throughput

0.513

High

748359

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.513

High

764068

RV167
Reduced viability upon starvation protein 167

1

0

High-throughput

0.513

High

774243

SPC24
Kinetochore protein SPC24

1

0

High-throughput

0.513

High

378357

LEU3
3-isopropylmalate dehydrogenase

1

2

High-throughput

0.500

High

566604

VATA
V-type proton ATPase catalytic subunit A

1

2

High-throughput

0.489

High

689353

ARP2
Actin-related protein 2

1

1

High-throughput

0.489

High

774250

MED11
Mediator of RNA polymerase II transcription subunit 11

1

0

High-throughput

0.486

High

628986

SCJ1
DnaJ-related protein SCJ1

1

0

High-throughput

0.479

High

774230

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.479

High

774236

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

0

High-throughput

0.479

High

774237

ACT
Actin

1

0

High-throughput

0.479

High

543868

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.479

High

662419

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

756332

DNA2
DNA replication ATP-dependent helicase/nuclease DNA2 [Includes: DNA replication nuclease DNA2

1

1

High-throughput

0.479

High

774240

RLI1
Translation initiation factor RLI1

1

1

High-throughput

0.479

High

774245

NTH2
Endonuclease III homolog 2

1

2

High-throughput

0.479

High

774248

MLH3
DNA mismatch repair protein MLH3

1

3

High-throughput

0.479

High

358100

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.458

High

407098

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

425126

LEUC
3-isopropylmalate dehydratase

1

0

Small-scale

0.458

High

631919

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

706312

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

729948

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

746148

PLPHP
Pyridoxal phosphate homeostasis protein

1

0

High-throughput

0.458

High

763425

MET10
Sulfite reductase [NADPH] flavoprotein component

1

0

High-throughput

0.458

High

774232

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

774238

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

774242

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

774246

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

774249

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

366404

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.445

High

491441

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

556092

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.445

High

617421

NAR1
Cytosolic Fe-S cluster assembly factor NAR1

1

2

Small-scale

0.445

High

692542

ZUO1
Zuotin

1

1

High-throughput

0.445

High

694832

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

761369

XDJ1
DnaJ protein homolog XDJ1

1

2

High-throughput

0.445

High

713700

NOT4
General negative regulator of transcription subunit 4

1

0

High-throughput

0.438

High

774235

MDG1
Signal transduction protein MDG1

1

0

High-throughput

0.438

High

774239

CWC27
Peptidyl-prolyl isomerase CWC27

1

0

High-throughput

0.438

High

774247

YP191
Ubiquitin carboxyl-terminal hydrolase MIY1

1

0

High-throughput

0.438

High

360906

TBB
Tubulin beta chain

1

0

High-throughput

0.426

High

424554

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

440892

ARO1
Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase

1

0

High-throughput

0.426

High

605232

AFT1
Iron-regulated transcriptional activator AFT1

1

0

High-throughput

0.426

High

687396

EF2
Elongation factor 2

1

0

High-throughput

0.426

High

754466

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

773655

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.426

High

774229

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.426

High

774231

YAE1
Protein YAE1

1

0

Small-scale

0.426

High

774233

MPA43
Protein MPA43

1

0

High-throughput

0.426

High

774234

LTO1
Protein LTO1

1

0

Small-scale

0.426

High

774241

YM44
Uncharacterized protein YMR178W

1

0

High-throughput

0.426

High

774228

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

2

High-throughput

0.407

High

448503

PRTB
Cerevisin

1

0

High-throughput

0.279

Low

745697

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

757988

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024