HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: RS16 (P62249)
Small ribosomal subunit protein uS9 (40S ribosomal protein S16)
Gene: RPS16

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21182205
Identification Methods	affinity chromatography technology, cosedimentation through density gradient
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 595 Hs			1 146
+	Hs
		369391 ESR1_HUMAN (1-595): 0: 599: 100.00		RT09_HUMAN (14-146): 4.67e-45: 153: 34.07
+	Hs
		908058 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		RS16_HUMAN (1-146): 8.71e-71: 211: 100.00
+	Hs
		320192 ERR2_HUMAN (92-547): 4.3e-116: 354: 34.86		RS16_HUMAN (1-146): 8.71e-71: 211: 100.00
+	Hs
		948648 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		RT09_HUMAN (14-146): 4.67e-45: 153: 34.07
+	Mm
		509280 RARA_MOUSE (81-545): 8.36e-104: 323: 22.37		RS16_MOUSE (1-146): 8.71e-71: 211: 100.00
+	Hs
		377250 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		RT09_HUMAN (14-146): 4.67e-45: 153: 34.07
+	Hs
		487295 ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16		RS16_HUMAN (1-146): 8.71e-71: 211: 100.00
+	Hs
		487331 ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16		RT09_HUMAN (14-146): 4.67e-45: 153: 34.07