Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: CTBP1 (Q13363)
C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-)
Gene: CTBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.66 0.60 0.633

The method score is based on:

Property Details
Experiments 23403292, 31527615, unassigned1953
Identification Methods affinity chromatography technology, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001221 - transcription coregulator binding
GO:0001222 - transcription corepressor binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus
and 2 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 595
Hs

1 440
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024