Protein: ANGT
Angiotensinogen (Serpin A8) [Cleaved into: Angiotensin-1 (Angiotensin 1-10) (Angiotensin I) (Ang I); Angiotensin-2 (Angiotensin 1-8) (Angiotensin II) (Ang II); Angiotensin-3 (Angiotensin 2-8) (Angiotensin III) (Ang III) (Des-Asp[1]-angiotensin II); Angiotensin-4 (Angiotensin 3-8) (Angiotensin IV) (Ang IV); Angiotensin 1-9; Angiotensin 1-7; Angiotensin 1-5; Angiotensin 1-4]

Gene: ANGT, AGT
Organism: Homo sapiens
Interactions: 44
UniProt ID: P01019

Gene Ontology (top 5):
GO:0001558 - regulation of cell growth
GO:0001819 - positive regulation of cytokine production
GO:0001822 - kidney development
GO:0001974 - blood vessel remodeling
GO:0002016 - regulation of blood volume by renin-angiotensin

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

366599

RENI
Renin

2

1

Small-scale

0.834

High

210638

KLK10
Kallikrein-10

1

20

High-throughput

0.691

High

369556

ACE2
Angiotensin-converting enzyme 2

3

3

Small-scale

0.660

High

369534

ACE
Angiotensin-converting enzyme

3

3

Small-scale

0.646

High

369533

BIP
Endoplasmic reticulum chaperone BiP

2

11

High-throughput

0.628

High

369535

CALX
Calnexin

2

7

High-throughput

0.628

High

369542

AGTR2
Type-2 angiotensin II receptor

2

12

Small-scale

0.595

High

369548

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.553

High

217681

TGON2
Trans-Golgi network integral membrane protein 2

2

3

High-throughput

0.549

High

369557

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

2

8

High-throughput

0.533

High

369553

Q8TAS3
PRRG2 protein

1

11

High-throughput

0.515

High

369545

GRB2
Growth factor receptor-bound protein 2

1

10

High-throughput

0.508

High

292509

RENR
Renin receptor

1

6

Small-scale

0.501

High

369531

HS90A
Heat shock protein HSP 90-alpha

1

4

Small-scale

0.501

High

369532

NEP
Neprilysin

1

2

Small-scale

0.501

High

369540

ECE1
Endothelin-converting enzyme 1

1

2

Small-scale

0.501

High

369546

EWS
RNA-binding protein EWS

1

5

High-throughput

0.494

High

369547

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

7

High-throughput

0.489

High

369549

CIR1
Corepressor interacting with RBPJ 1

1

2

High-throughput

0.489

High

369560

PHF11
PHD finger protein 11

1

8

High-throughput

0.489

High

369530

P53
Cellular tumor antigen p53

1

3

Small-scale

0.481

High

369558

ITSN2
Intersectin-2

1

6

High-throughput

0.481

High

369561

LCAP
Leucyl-cystinyl aminopeptidase

1

0

Small-scale

0.480

High

369529

A2MG
Alpha-2-macroglobulin

1

1

High-throughput

0.479

High

369536

AGTR1
Type-1 angiotensin II receptor

1

11

Small-scale

0.479

High

369537

STAT3
Signal transducer and activator of transcription 3

1

1

Small-scale

0.479

High

369538

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

1

Small-scale

0.479

High

369541

SOX2
Transcription factor SOX-2

1

8

High-throughput

0.479

High

143780

NDKM
Nucleoside diphosphate kinase, mitochondrial

1

1

High-throughput

0.470

High

162423

ANM5
Protein arginine N-methyltransferase 5

1

1

High-throughput

0.470

High

369551

VKORL
Vitamin K epoxide reductase complex subunit 1-like protein 1

1

1

High-throughput

0.470

High

369559

EI2BD
Translation initiation factor eIF2B subunit delta

1

1

High-throughput

0.470

High

369562

SNX12
Sorting nexin-12

1

1

High-throughput

0.470

High

369539

PCP
Lysosomal Pro-X carboxypeptidase

1

5

Small-scale

0.445

High

369554

GSDMB
Gasdermin-B

1

1

High-throughput

0.439

High

105062

APRIO
Alternative prion protein

1

6

High-throughput

0.437

High

360696

COX3
Cytochrome c oxidase subunit 3

1

3

Small-scale

0.437

High

369543

GPC3
Glypican-3

1

3

High-throughput

0.407

High

369544

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

9

High-throughput

0.407

High

369555

Q96T11
Receptor-interacting serine/threonine-protein kinase 4

1

9

High-throughput

0.407

High

328217

NDUA3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

2

0

High-throughput

0.328

High

91517

C9J082
Nephrocystin 1

1

0

High-throughput

0.268

Low

369550

SLN12
Ribonuclease SLFN12

1

0

High-throughput

0.268

Low

369552

T185A
Transmembrane protein 185A

1

0

High-throughput

0.268

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025