HitPredict

Interactor 1: A2MG (P01023)
Alpha-2-macroglobulin (Alpha-2-M) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5)
Gene: A2M

Interactor 2: APOE (P02649)
Apolipoprotein E (Apo-E)
Gene: APOE

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.60 0.640

The method score is based on:

Property Details
Experiments 9831625, 21163940
Identification Methods affinity chromatography technology, pull down, two hybrid, two hybrid array
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005102 - signaling receptor binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0019899 - enzyme binding
GO:0070062 - extracellular exosome
and 1 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1474
Hs

1 317
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025