Interactor 1: TIMP1 (P01033)
Metalloproteinase inhibitor 1 (Erythroid-potentiating activity) (EPA) (Fibroblast collagenase inhibitor) (Collagenase inhibitor) (Tissue inhibitor of metalloproteinases 1) (TIMP-1)
Gene: TIMP1

Interactor 2: TIMP2 (P16035)
Metalloproteinase inhibitor 2 (CSC-21K) (Tissue inhibitor of metalloproteinases 2) (TIMP-2)
Gene: TIMP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 39238192
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002020 - protease binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0008191 - metalloendopeptidase inhibitor activity
GO:0008270 - zinc ion binding
and 6 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 207
Hs

1 220
+ Hs
+ Hs
+ Hs

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Last updated: 11Aug2025