Protein: KPRB
Phosphoribosyl pyrophosphate synthase-associated protein 2 (PRPP synthase-associated protein 2) (41 kDa phosphoribosypyrophosphate synthetase-associated protein) (PAP41)

Gene: KPRB, PRPSAP2
Organism: Homo sapiens
Interactions: 97
UniProt ID: O60256

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0002189 - ribose phosphate diphosphokinase complex
GO:0004749 - ribose phosphate diphosphokinase activity
GO:0004857 - enzyme inhibitor activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

225860

PRPS1
Ribose-phosphate pyrophosphokinase 1

6

17

High-throughput

0.950

High

225834

PRPS2
Ribose-phosphate pyrophosphokinase 2

5

17

High-throughput

0.926

High

225876

KPRA
Phosphoribosyl pyrophosphate synthase-associated protein 1

5

16

High-throughput

0.926

High

225844

PRPS3
Ribose-phosphate pyrophosphokinase 3

2

16

High-throughput

0.811

High

225816

KPRB
Phosphoribosyl pyrophosphate synthase-associated protein 2

2

16

High-throughput

0.783

High

225836

CCNB1
G2/mitotic-specific cyclin-B1

2

0

High-throughput

0.602

High

225863

1433E
14-3-3 protein epsilon

2

3

Small-scale

0.601

High

225891

LZTR1
Leucine-zipper-like transcriptional regulator 1

2

6

High-throughput

0.574

High

225899

SNAG
Gamma-soluble NSF attachment protein

2

4

High-throughput

0.574

High

225910

NS1BP
Influenza virus NS1A-binding protein

2

4

High-throughput

0.574

High

181747

SOCS1
Suppressor of cytokine signaling 1

2

14

High-throughput

0.571

High

225819

DOK2
Docking protein 2

2

4

High-throughput

0.571

High

225820

SH3L1
Adapter SH3BGRL

2

3

High-throughput

0.571

High

225827

KPCG
Protein kinase C gamma type

2

15

High-throughput

0.571

High

225829

FYN
Tyrosine-protein kinase Fyn

2

10

High-throughput

0.571

High

225830

HCK
Tyrosine-protein kinase HCK

2

10

High-throughput

0.571

High

225837

VAV
Proto-oncogene vav

2

3

High-throughput

0.571

High

225839

NCK1
SH2/SH3 adapter protein NCK1

2

14

High-throughput

0.571

High

225840

KPCA
Protein kinase C alpha type

2

10

High-throughput

0.571

High

225842

RAB5A
Ras-related protein Rab-5A

2

3

High-throughput

0.571

High

225843

RASA1
Ras GTPase-activating protein 1

2

3

High-throughput

0.571

High

225848

PEBP1
Phosphatidylethanolamine-binding protein 1

2

1

High-throughput

0.571

High

225861

CDC42
Cell division control protein 42 homolog

2

8

High-throughput

0.571

High

225864

RAC1
Ras-related C3 botulinum toxin substrate 1

2

7

High-throughput

0.571

High

225866

KPCE
Protein kinase C epsilon type

2

10

High-throughput

0.571

High

225869

PTN12
Tyrosine-protein phosphatase non-receptor type 12

2

3

High-throughput

0.571

High

225872

PAK1
Serine/threonine-protein kinase PAK 1

2

4

High-throughput

0.571

High

225873

MK07
Mitogen-activated protein kinase 7

2

9

High-throughput

0.571

High

225878

KPCD1
Serine/threonine-protein kinase D1

2

14

High-throughput

0.571

High

225818

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

5

High-throughput

0.536

High

225833

TOP1
DNA topoisomerase 1

1

2

High-throughput

0.536

High

225895

CSN5
COP9 signalosome complex subunit 5

1

7

High-throughput

0.536

High

225897

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

1

3

High-throughput

0.536

High

225847

ELK4
ETS domain-containing protein Elk-4

2

5

High-throughput

0.521

High

225854

PAXI
Paxillin

2

4

High-throughput

0.521

High

225858

CAV2
Caveolin-2

2

7

High-throughput

0.521

High

225867

CAV1
Caveolin-1

2

7

High-throughput

0.521

High

225888

ABI1
Abl interactor 1

2

3

High-throughput

0.521

High

225890

SH2D3
SH2 domain-containing protein 3C

2

15

High-throughput

0.521

High

225865

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.513

High

225875

CAPR1
Caprin-1

1

0

High-throughput

0.513

High

225896

DCNL1
DCN1-like protein 1

1

0

High-throughput

0.513

High

225907

RTCB
RNA-splicing ligase RtcB homolog

1

0

High-throughput

0.513

High

225826

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

225831

PARP1
Poly [ADP-ribose] polymerase 1

1

4

High-throughput

0.489

High

225845

CBL
E3 ubiquitin-protein ligase CBL

1

2

High-throughput

0.489

High

225852

CAPZB
F-actin-capping protein subunit beta

1

2

High-throughput

0.489

High

225859

SNAA
Alpha-soluble NSF attachment protein

1

1

High-throughput

0.489

High

225871

SSRP1
FACT complex subunit SSRP1

1

2

High-throughput

0.489

High

225886

SFPA2
Pulmonary surfactant-associated protein A2

1

1

High-throughput

0.489

High

225906

NTNG1
Netrin-G1

1

1

High-throughput

0.489

High

225909

WIF1
Wnt inhibitory factor 1

1

1

High-throughput

0.489

High

225817

PRKN
E3 ubiquitin-protein ligase parkin

1

6

High-throughput

0.479

High

225822

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.479

High

225823

SNAI1
Zinc finger protein SNAI1

1

3

High-throughput

0.479

High

225825

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.479

High

225832

BIP
Endoplasmic reticulum chaperone BiP

1

2

High-throughput

0.479

High

225835

TCTP
Translationally-controlled tumor protein

1

1

High-throughput

0.479

High

225851

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

225853

TISD
mRNA decay activator protein ZFP36L2

1

3

High-throughput

0.479

High

225856

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

2

High-throughput

0.479

High

225857

CDK7
Cyclin-dependent kinase 7

1

5

High-throughput

0.479

High

225862

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

4

High-throughput

0.479

High

225868

UBXN1
UBX domain-containing protein 1

1

3

High-throughput

0.479

High

225870

KPCZ
Protein kinase C zeta type

1

11

High-throughput

0.479

High

225884

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.479

High

225885

LYRIC
Protein LYRIC

1

1

Small-scale

0.479

High

225894

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

225900

ANM1
Protein arginine N-methyltransferase 1

1

2

High-throughput

0.479

High

225902

PKHA4
Pleckstrin homology domain-containing family A member 4

1

12

High-throughput

0.479

High

225903

PKHA2
Pleckstrin homology domain-containing family A member 2

1

3

Small-scale

0.479

High

225905

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

225908

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

5

Small-scale

0.479

High

225881

H2B2F
Histone H2B type 2-F

1

2

High-throughput

0.470

High

225824

NSD2
Histone-lysine N-methyltransferase NSD2

1

0

Small-scale

0.458

High

225821

PR15A
Protein phosphatase 1 regulatory subunit 15A

1

1

High-throughput

0.445

High

225841

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

6

High-throughput

0.445

High

225882

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

3

High-throughput

0.445

High

225892

ENDOV
Endonuclease V

1

0

High-throughput

0.438

High

225838

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

225846

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

225850

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

225874

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.437

High

225877

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

4

High-throughput

0.437

High

225879

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

2

High-throughput

0.437

High

225880

EMC4
ER membrane protein complex subunit 4

1

3

High-throughput

0.437

High

225828

JUN
Transcription factor Jun

1

4

High-throughput

0.407

High

225883

PKHA7
Pleckstrin homology domain-containing family A member 7

1

9

High-throughput

0.407

High

225849

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

2

0

High-throughput

0.328

High

225855

FNTB
Protein farnesyltransferase subunit beta

2

0

High-throughput

0.328

High

225889

GLT16
Polypeptide N-acetylgalactosaminyltransferase 16

2

0

High-throughput

0.328

High

225887

TEX11
Testis-expressed protein 11

2

0

High-throughput

0.316

High

225893

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

1

0

High-throughput

0.279

Low

225898

DOCK7
Dedicator of cytokinesis protein 7

1

0

High-throughput

0.279

Low

225904

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

1

0

High-throughput

0.279

Low

225901

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024