HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: MSI2H (Q96DH6)
RNA-binding protein Musashi homolog 2 (Musashi-2)
Gene: MSI2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33731348
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 595 Hs			1 328
+	Hs
		369222 ESR1_HUMAN (1-595): 0: 599: 100.00		ROA3_HUMAN (15-193): 6.74e-76: 239: 41.99
+	Hs
		368852 ESR1_HUMAN (1-595): 0: 599: 100.00		ROA1_HUMAN (12-193): 3.31e-74: 234: 41.18
+	Hs
		369578 ESR1_HUMAN (1-595): 0: 599: 100.00		HNRPD_HUMAN (6-289): 3.47e-55: 185: 35.21
+	Hs
		369725 ESR1_HUMAN (1-595): 0: 599: 100.00		RA1L2_HUMAN (9-320): 1.9e-54: 182: 28.57
+	Hs
		370290 ESR1_HUMAN (1-595): 0: 599: 100.00		ROAA_HUMAN (2-289): 1.19e-53: 180: 36.21
+	Hs
		369739 ESR1_HUMAN (1-595): 0: 599: 100.00		PAP1L_HUMAN (12-278): 7.2e-45: 163: 17.10
+	Hs
		369534 ESR1_HUMAN (1-595): 0: 599: 100.00		PABP4_HUMAN (12-264): 4.39e-43: 158: 17.26
+	Hs
		368987 ESR1_HUMAN (1-595): 0: 599: 100.00		ROA2_HUMAN (96-206): 4.25e-26: 108: 33.33
+	Hs
		368886 ESR1_HUMAN (1-595): 0: 599: 100.00		PABP1_HUMAN (100-190): 1.7e-15: 79.3: 18.48
+	Hs
		370422 ESR1_HUMAN (1-595): 0: 599: 100.00		PABP3_HUMAN (100-190): 1.19e-13: 73.5: 17.39
+	Hs
		377031 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		ROA1_HUMAN (12-193): 3.31e-74: 234: 41.18
+	Hs
		1119140 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		PAP1L_HUMAN (12-278): 7.2e-45: 163: 17.10
+	Hs
		1031409 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		PABP4_HUMAN (12-264): 4.39e-43: 158: 17.26
+	Hs
		377317 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		HNRPD_HUMAN (6-289): 3.47e-55: 185: 35.21
+	Hs
		782537 HNF4A_HUMAN (146-592): 2.13e-118: 361: 20.58		PABP4_HUMAN (12-264): 4.39e-43: 158: 17.26
+	Hs
		609976 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		ROA2_HUMAN (96-206): 4.25e-26: 108: 33.33
+	Hs
		162100 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		HNRDL_HUMAN (72-204): 1e-19: 91: 28.57
+	Hs
		1269600 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		PABP3_HUMAN (100-190): 1.19e-13: 73.5: 17.39
+	Hs
		161929 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		HNRDL_HUMAN (72-204): 1e-19: 91: 28.57
+	Hs
		516359 NR4A1_HUMAN (64-549): 2.81e-105: 331: 24.54		PABP1_HUMAN (100-190): 1.7e-15: 79.3: 18.48