HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: SCAFB (Q99590)
Protein SCAF11 (CTD-associated SR protein 11) (Renal carcinoma antigen NY-REN-40) (SC35-interacting protein 1) (SR-related and CTD-associated factor 11) (SRSF2-interacting protein) (Serine/arginine-rich splicing factor 2-interacting protein) (Splicing factor, arginine/serine-rich 2-interacting protein) (Splicing regulatory protein 129) (SRrp129)
Gene: SCAF11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31527615, unassigned1953
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 595 Hs			1 1463
+	Hs
		1269444 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		SCAFB_HUMAN (1-1463): 0: 657: 100.00
+	Hs
		370417 ESR1_HUMAN (1-595): 0: 599: 100.00		TARA_HUMAN (259-1434): 1.26e-65: 248: 9.20
+	Hs
		370600 ESR1_HUMAN (1-595): 0: 599: 100.00		PHRF1_HUMAN (37-1419): 2.87e-54: 211: 10.71
+	Hs
		370451 ESR1_HUMAN (1-595): 0: 599: 100.00		SFR19_HUMAN (416-1446): 8.8e-43: 173: 14.16
+	Hs
		369909 ESR1_HUMAN (1-595): 0: 599: 100.00		RBBP6_HUMAN (306-1122): 4.56e-26: 119: 11.74
+	Hs
		369607 ESR1_HUMAN (1-595): 0: 599: 100.00		MDC1_HUMAN (212-1082): 2.36e-25: 117: 9.88
+	Hs
		369815 ESR1_HUMAN (1-595): 0: 599: 100.00		NIPBL_HUMAN (305-1055): 3.43e-19: 96.9: 9.37
+	Hs
		370263 ESR1_HUMAN (1-595): 0: 599: 100.00		MINT_HUMAN (292-1220): 3.07e-10: 67.6: 8.93
+	Hs
		370728 ESR1_HUMAN (1-595): 0: 599: 100.00		SRRM2_HUMAN (240-1372): 3.69e-10: 67.4: 7.85
+	Hs
		370105 ESR1_HUMAN (1-595): 0: 599: 100.00		TITIN_HUMAN (986-1460): 9.74e-10: 65.8: 9.62
+	Hs
		1269591 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		TARA_HUMAN (259-1434): 1.26e-65: 248: 9.20
+	Hs
		1269801 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		PHRF1_HUMAN (37-1419): 2.87e-54: 211: 10.71
+	Hs
		1269627 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		SFR19_HUMAN (416-1446): 8.8e-43: 173: 14.16
+	Hs
		1191700 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		RBBP6_HUMAN (306-1122): 4.56e-26: 119: 11.74
+	Hs
		1056909 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		MDC1_HUMAN (212-1082): 2.36e-25: 117: 9.88
+	Hs
		1154059 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		NIPBL_HUMAN (305-1055): 3.43e-19: 96.9: 9.37
+	Hs
		517813 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		NFH_HUMAN (923-1439): 9.8e-11: 68.8: 8.70
+	Hs
		1269948 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		SRRM2_HUMAN (240-1372): 3.69e-10: 67.4: 7.85
+	Hs
		1264774 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		TITIN_HUMAN (986-1460): 9.74e-10: 65.8: 9.62
+	Hs
		1186078 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		MICA3_HUMAN (304-1133): 9.57e-10: 65.7: 11.03