HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: RBMX2 (Q9Y388)
RNA-binding motif protein, X-linked 2
Gene: RBMX2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31527615, unassigned1953
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 595 Hs			1 322
+	Hs
		369739 ESR1_HUMAN (1-595): 0: 599: 100.00		PAP1L_HUMAN (3-312): 9.93e-63: 211: 12.09
+	Hs
		369064 ESR1_HUMAN (1-595): 0: 599: 100.00		TIA1_HUMAN (31-282): 2.91e-42: 152: 14.49
+	Hs
		369646 ESR1_HUMAN (1-595): 0: 599: 100.00		NONO_HUMAN (25-310): 3.8e-38: 142: 15.33
+	Hs
		370404 ESR1_HUMAN (1-595): 0: 599: 100.00		CSTFT_HUMAN (38-124): 2.53e-34: 133: 36.78
+	Hs
		369602 ESR1_HUMAN (1-595): 0: 599: 100.00		RBM39_HUMAN (37-114): 4.65e-25: 106: 32.05
+	Hs
		368886 ESR1_HUMAN (1-595): 0: 599: 100.00		PABP1_HUMAN (7-227): 4.66e-23: 101: 12.29
+	Hs
		369534 ESR1_HUMAN (1-595): 0: 599: 100.00		PABP4_HUMAN (2-208): 7.82e-23: 100: 11.71
+	Hs
		370422 ESR1_HUMAN (1-595): 0: 599: 100.00		PABP3_HUMAN (7-272): 1.03e-22: 100: 10.92
+	Hs
		369421 ESR1_HUMAN (1-595): 0: 599: 100.00		TIAR_HUMAN (5-139): 1.24e-15: 78.7: 17.04
+	Hs
		1119140 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		PAP1L_HUMAN (3-312): 9.93e-63: 211: 12.09
+	Hs
		1269993 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		RBMX2_HUMAN (1-322): 3.9e-45: 158: 100.00
+	Hs
		680471 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		TIA1_HUMAN (31-282): 2.91e-42: 152: 14.49
+	Hs
		703423 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		CSTF2_HUMAN (38-124): 2.52e-34: 133: 36.78
+	Hs
		587171 RXRA_HUMAN (65-551): 4.55e-127: 383: 26.47		NONO_HUMAN (25-310): 3.8e-38: 142: 15.33
+	Mm
		139022 ESR2_MOUSE (22-582): 1.15e-136: 410: 45.81		RBM39_MOUSE (37-114): 4.52e-25: 107: 32.05
+	Hs
		1054478 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		RBM39_HUMAN (37-114): 4.65e-25: 106: 32.05
+	Hs
		1031409 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		PABP4_HUMAN (2-208): 7.82e-23: 100: 11.71
+	Hs
		1269600 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		PABP3_HUMAN (7-272): 1.03e-22: 100: 10.92
+	Hs
		963552 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		TIAR_HUMAN (5-139): 1.24e-15: 78.7: 17.04
+	Hs
		782537 HNF4A_HUMAN (146-592): 2.13e-118: 361: 20.58		PABP4_HUMAN (2-208): 7.82e-23: 100: 11.71