Protein: CENPO
Centromere protein O (CENP-O) (Interphase centromere complex protein 36)

Gene: CENPO
Organism: Homo sapiens
Interactions: 45
UniProt ID: Q9BU64

Gene Ontology (top 5):
GO:0000939 - inner kinetochore
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0007059 - chromosome segregation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1234737

CENPP
Centromere protein P

8

0

Small-scale

0.923

High

1103023

CENPR
Centromere protein R

6

0

Small-scale

0.897

High

1392631

CENPN
Centromere protein N

3

0

Small-scale

0.803

High

1259018

CENPU
Centromere protein U

6

0

Small-scale

0.702

High

1271991

CENPQ
Centromere protein Q

5

0

Small-scale

0.688

High

370772

FOS
Protein c-Fos

2

2

High-throughput

0.614

High

1366696

CENPI
Centromere protein I

2

1

Small-scale

0.611

High

1413955

CENPH
Centromere protein H

2

1

Small-scale

0.611

High

921056

FOSB
Protein FosB

2

2

High-throughput

0.606

High

1147743

MTFR1
Mitochondrial fission regulator 1

2

0

High-throughput

0.585

High

1413957

CENPM
Centromere protein M

2

0

Small-scale

0.585

High

1041846

CENPC
Centromere protein C

1

1

High-throughput

0.536

High

1232335

Q6FG41
Protein c-Fos

1

2

High-throughput

0.515

High

70876

CENPX
Centromere protein X

1

0

High-throughput

0.513

High

596325

H12
Histone H1.2

1

0

High-throughput

0.513

High

627404

AT2B1
Plasma membrane calcium-transporting ATPase 1

1

0

High-throughput

0.513

High

785410

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.513

High

828440

PEX19
Peroxisomal biogenesis factor 19

1

0

High-throughput

0.513

High

859975

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.513

High

944159

WDR4
tRNA

1

0

High-throughput

0.513

High

1062098

SRSF4
Serine/arginine-rich splicing factor 4

1

0

High-throughput

0.513

High

1097727

STK3
Serine/threonine-protein kinase 3

1

0

High-throughput

0.513

High

1324634

CENPS
Centromere protein S

1

0

High-throughput

0.513

High

1340608

SMS2
Phosphatidylcholine:ceramide cholinephosphotransferase 2

1

0

High-throughput

0.513

High

1361748

DGCR8
Microprocessor complex subunit DGCR8

1

0

High-throughput

0.513

High

1385064

CENPT
Centromere protein T

1

0

High-throughput

0.513

High

1412117

CENPK
Centromere protein K

1

0

High-throughput

0.513

High

1287825

PABP2
Polyadenylate-binding protein 2

1

1

High-throughput

0.479

High

920248

PLK1
Serine/threonine-protein kinase PLK1

1

0

High-throughput

0.458

High

1339876

KNL1
Outer kinetochore KNL1 complex subunit KNL1

1

0

Small-scale

0.458

High

1413956

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.458

High

108079

G3V4T2
Polyadenylate-binding protein 2

1

1

High-throughput

0.445

High

272744

BRE1B
E3 ubiquitin-protein ligase BRE1B

1

0

High-throughput

0.438

High

883674

CENPA
Histone H3-like centromeric protein A

1

0

Small-scale

0.426

High

1396571

C170L
Cep170-like protein

3

0

High-throughput

0.336

High

1279970

NECA2
N-terminal EF-hand calcium-binding protein 2

2

0

High-throughput

0.330

High

1395905

ARL5B
ADP-ribosylation factor-like protein 5B

2

0

High-throughput

0.318

High

1413958

DCDC2
Doublecortin domain-containing protein 2

2

0

High-throughput

0.316

High

208137

PLXB1
Plexin-B1

1

0

High-throughput

0.279

Low

280318

SC22B
Vesicle-trafficking protein SEC22b

1

0

High-throughput

0.279

Low

706285

S10A2
Protein S100-A2

1

0

High-throughput

0.279

Low

1127478

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

1413959

S39AA
Zinc transporter ZIP10

1

0

High-throughput

0.279

Low

1413960

MFHA1
Malignant fibrous histiocytoma-amplified sequence 1

1

0

High-throughput

0.279

Low

215755

ERI3
ERI1 exoribonuclease 3

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025