Protein: FOSB
Protein FosB (FosB proto-oncogene, AP-1 transcription factor subunit) (G0/G1 switch regulatory protein 3) (Transcription factor AP-1 subunit FosB)

Gene: FOSB
Organism: Homo sapiens
Interactions: 43
UniProt ID: P53539

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

603631

JUNB
Transcription factor JunB

5

20

Small-scale

0.927

High

429570

JUN
Transcription factor Jun

4

20

Small-scale

0.908

High

583505

ATF2
Cyclic AMP-dependent transcription factor ATF-2

3

20

High-throughput

0.858

High

921037

CREB5
Cyclic AMP-responsive element-binding protein 5

3

20

High-throughput

0.858

High

921044

NF2L2
Nuclear factor erythroid 2-related factor 2

1

20

Small-scale

0.778

High

370610

FOS
Protein c-Fos

1

20

High-throughput

0.691

High

605063

JUND
Transcription factor JunD

1

20

High-throughput

0.691

High

605245

ATF7
Cyclic AMP-dependent transcription factor ATF-7

1

20

High-throughput

0.691

High

921045

MIDN
Midnolin

2

1

High-throughput

0.611

High

210252

PHF1
PHD finger protein 1

2

2

High-throughput

0.606

High

222042

NCK2
Cytoplasmic protein NCK2

2

5

High-throughput

0.606

High

224958

TLX3
T-cell leukemia homeobox protein 3

2

10

High-throughput

0.606

High

638839

AGT1
Alanine--glyoxylate aminotransferase

2

3

High-throughput

0.606

High

921035

PO6F2
POU domain, class 6, transcription factor 2

2

12

High-throughput

0.606

High

921039

TLE5
TLE family member 5

2

6

High-throughput

0.606

High

921042

VEZF1
Vascular endothelial zinc finger 1

2

7

High-throughput

0.606

High

921043

CASL
Enhancer of filamentation 1

2

8

High-throughput

0.606

High

921046

POGZ
Pogo transposable element with ZNF domain

2

4

High-throughput

0.606

High

921053

TET5B
Terminal nucleotidyltransferase 5B

2

1

High-throughput

0.606

High

921056

CENPO
Centromere protein O

2

2

High-throughput

0.606

High

921058

GLIS2
Zinc finger protein GLIS2

2

4

High-throughput

0.606

High

921059

FOXP3
Forkhead box protein P3

2

5

High-throughput

0.606

High

921062

CYH4
Cytohesin-4

2

10

High-throughput

0.606

High

921051

F222B
Protein FAM222B

2

0

High-throughput

0.580

High

921054

ZC3HA
Zinc finger CCCH domain-containing protein 10

2

0

High-throughput

0.580

High

921036

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

2

6

High-throughput

0.553

High

921060

ENKD1
Enkurin domain-containing protein 1

2

1

High-throughput

0.553

High

921049

STK40
Serine/threonine-protein kinase 40

1

15

High-throughput

0.536

High

921050

COP1
E3 ubiquitin-protein ligase COP1

1

15

High-throughput

0.536

High

921055

TRIB1
Tribbles homolog 1

1

14

High-throughput

0.536

High

921057

PCGF6
Polycomb group RING finger protein 6

1

15

High-throughput

0.536

High

921063

TSR3
18S rRNA aminocarboxypropyltransferase

1

1

High-throughput

0.536

High

85473

B7ZLY0
PHC2 protein

1

8

High-throughput

0.515

High

921040

EP300
Histone acetyltransferase p300

1

20

Small-scale

0.501

High

921061

SRA1
Steroid receptor RNA activator 1

1

5

Small-scale

0.501

High

921064

DNM3L
DNA

1

9

Small-scale

0.501

High

921038

MECOM
Histone-lysine N-methyltransferase MECOM

1

12

Small-scale

0.500

High

921041

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

3

High-throughput

0.489

High

921048

PHC2
Polyhomeotic-like protein 2

1

7

High-throughput

0.481

High

738961

ELF1
ETS-related transcription factor Elf-1

1

20

Small-scale

0.479

High

921052

CBP
CREB-binding protein

1

20

Small-scale

0.479

High

347595

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

921047

F90A1
Protein FAM90A1

2

0

High-throughput

0.316

High


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Last updated: 11Aug2025