Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: TFR1 (P02786)
Transferrin receptor protein 1 (TR) (TfR) (TfR1) (Trfr) (T9) (p90) (CD antigen CD71) [Cleaved into: Transferrin receptor protein 1, serum form (sTfR)]
Gene: TFRC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 29467282, 36424410
Identification Methods affinity chromatography technology, proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0006879 - intracellular iron ion homeostasis
GO:0010628 - positive regulation of gene expression
GO:0043066 - negative regulation of apoptotic process
GO:0044877 - protein-containing complex binding
GO:0048471 - perinuclear region of cytoplasm
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 454
Hs

1 760
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025