HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: ANXA1 (P04083)
Annexin A1 (Annexin I) (Annexin-1) (Calpactin II) (Calpactin-2) (Chromobindin-9) (Lipocortin I) (Phospholipase A2 inhibitory protein) (p35) [Cleaved into: Annexin Ac2-26]
Gene: ANXA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	29467282, 35013218, 36424410
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0043066 - negative regulation of apoptotic process
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 346
+	Hs
		370945 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		ANXA2_HUMAN (1-346): 3.38e-164: 463: 51.01
+	Hs
		370978 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		ANXA5_HUMAN (33-346): 7.61e-162: 456: 43.63
+	Hs
		456602 TFEB_HUMAN (180-450): 2.12e-27: 116: 14.59		ANXA2_HUMAN (1-346): 3.38e-164: 463: 51.01
+	Hs
		371142 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		ANXA7_HUMAN (199-346): 1.48e-39: 147: 30.41