HitPredict

Interactor 1: CFAD (P03953)
Complement factor D (EC 3.4.21.46) (28 kDa adipocyte protein) (Adipsin) (C3 convertase activator) (Properdin factor D)
Gene: Cfd

Interactor 2: FBLN2 (P37889)
Fibulin-2 (FIBL-2)
Gene: FBLN2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	30550785
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FXa_inhibition~Trypsin
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 259 Mm			1 1221
+	Mm
		372179 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		LTBP1_MOUSE (844-1167): 2.74e-27: 122: 31.33
+	Hs
		1204963 KLK11_HUMAN (23-256): 1.47e-96: 285: 32.37		FRAS1_HUMAN (25-833): 1.13e-27: 124: 9.31
+	Hs
		1198216 TM11B_HUMAN (13-253): 7.08e-99: 296: 31.73		AGRE2_HUMAN (890-1127): 5.07e-24: 111: 32.84
+	Mm
		139744 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		MATN2_MOUSE (277-641): 3.44e-16: 86.3: 11.89
+	Mm
		372013 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		SNED1_MOUSE (63-448): 2.03e-14: 80.5: 8.65
+	Mm
		192824 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		NOTC2_MOUSE (32-518): 1.2e-13: 78.2: 10.64
+	Mm
		371934 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		LTBP3_MOUSE (48-637): 1.41e-13: 77.8: 10.75
+	Mm
		372120 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		FBLN3_MOUSE (736-981): 7.69e-12: 71.2: 31.20
+	Hs
		371464 KLKB1_HUMAN (3-256): 5.99e-100: 306: 30.30		FBN2_HUMAN (31-535): 1.14e-13: 78.6: 9.78
+	Mm
		372692 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		FBLN4_MOUSE (377-648): 6.74e-10: 65: 13.72
+	Mm
		371892 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		FBLN7_MOUSE (398-648): 6.87e-09: 61.8: 18.08
+	Hs
		980428 TM11B_HUMAN (13-253): 7.08e-99: 296: 31.73		NOTC2_HUMAN (32-514): 2.96e-13: 77.1: 10.93
+	Hs
		1198224 TM11B_HUMAN (13-253): 7.08e-99: 296: 31.73		JAG2_HUMAN (25-424): 1.8e-09: 64.4: 10.31
+	Hs
		1345092 TMPS4_HUMAN (9-252): 1.75e-97: 293: 35.06		JAG2_HUMAN (25-424): 1.8e-09: 64.4: 10.31
+	Hs
		409496 HEPS_HUMAN (15-259): 1.34e-98: 295: 30.68		FBLN1_HUMAN (140-571): 9.79e-09: 61.7: 7.62
+	Hs
		589611 KLK2_HUMAN (1-256): 3.23e-97: 287: 32.59		JAG2_HUMAN (25-424): 1.8e-09: 64.4: 10.31
+	Hs
		1329638 KLK15_HUMAN (16-256): 3.77e-97: 286: 36.61		JAG2_HUMAN (25-424): 1.8e-09: 64.4: 10.31
+	Hs
		486154 GRAB_HUMAN (24-250): 8.92e-44: 150: 34.48		NOTC1_HUMAN (24-810): 1.39e-33: 143: 10.21
+	Hs
		621376 CMA1_HUMAN (18-256): 4.69e-39: 137: 33.74		FRAS1_HUMAN (25-833): 1.13e-27: 124: 9.31
+	Mm
		378815 GRAB_MOUSE (24-250): 1.05e-42: 147: 33.62		NOTC1_MOUSE (25-461): 3.88e-09: 63.6: 8.82