HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: CACO2 (Q13137)
Calcium-binding and coiled-coil domain-containing protein 2 (Antigen nuclear dot 52 kDa protein) (Nuclear domain 10 protein NDP52) (Nuclear domain 10 protein 52) (Nuclear dot protein 52)
Gene: CALCOCO2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21150319
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 446
+	Hs
		372263 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		MRCKA_HUMAN (82-406): 1.73e-27: 118: 14.33
+	Hs
		371326 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		MYH10_HUMAN (75-437): 6.01e-11: 67.1: 13.17
+	Hs
		372722 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		MY18A_HUMAN (108-352): 6.96e-11: 66.7: 14.44
+	Hs
		372009 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		DCTN1_HUMAN (75-339): 2.67e-10: 64.7: 10.33
+	Hs
		371334 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		MYH11_HUMAN (81-361): 3.77e-09: 61.3: 13.68
+	Hs
		371325 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		MYH9_HUMAN (144-345): 7.97e-09: 60.2: 15.05
+	Hs
		896192 MXI1_HUMAN (321-450): 2.57e-29: 116: 27.69		CACO2_HUMAN (1-446): 2.19e-63: 213: 100.00
+	Hs
		405846 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		MYH10_HUMAN (75-437): 6.01e-11: 67.1: 13.17
+	Hs
		405845 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		MYH9_HUMAN (144-345): 7.97e-09: 60.2: 15.05