HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: I2BP2 (Q7Z5L9)
Interferon regulatory factor 2-binding protein 2 (IRF-2-binding protein 2) (IRF-2BP2)
Gene: IRF2BP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30415952, 25452129
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 587
+	Hs
		319081 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		SC24D_HUMAN (62-326): 3.23e-11: 68.6: 14.82
+	Hs
		274070 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		ANR17_HUMAN (65-500): 7.4e-10: 64.3: 11.96
+	Hs
		372755 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		PRG4_HUMAN (75-487): 1.19e-09: 63.6: 6.54
+	Hs
		371554 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		SC24C_HUMAN (58-335): 1.48e-09: 63.2: 11.51
+	Hs
		372262 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		OBSCN_HUMAN (132-501): 3.41e-09: 62.4: 12.06
+	Hs
		319082 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		SC24D_HUMAN (62-326): 3.23e-11: 68.6: 14.82
+	Hs
		274074 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		ANR17_HUMAN (65-500): 7.4e-10: 64.3: 11.96
+	Hs
		405937 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		SC24C_HUMAN (58-335): 1.48e-09: 63.2: 11.51