HitPredict

Interactor 1: MMP1 (P03956)
Interstitial collagenase (EC 3.4.24.7) (Fibroblast collagenase) (Matrix metalloproteinase-1) (MMP-1) [Cleaved into: 22 kDa interstitial collagenase; 27 kDa interstitial collagenase]
Gene: MMP1

Interactor 2: ATF3 (P18847)
Cyclic AMP-dependent transcription factor ATF-3 (cAMP-dependent transcription factor ATF-3) (Activating transcription factor 3)
Gene: ATF3

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	18802113
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 469 Hs			1 181
+	Hs
		345276 MMP1_HUMAN (1-469): 0: 663: 100.00		FOS_HUMAN (14-158): 2.36e-25: 102: 26.25
+	Hs
		372725 MMP1_HUMAN (1-469): 0: 663: 100.00		FOSL1_HUMAN (42-169): 1.11e-22: 93.4: 26.76
+	Hs
		345361 MMP13_HUMAN (4-466): 0: 626: 47.65		FOS_HUMAN (14-158): 2.36e-25: 102: 26.25
+	Mm
		345605 MMP13_MOUSE (1-466): 0: 624: 47.89		FOS_MOUSE (13-158): 2e-24: 99.5: 26.71
+	Hs
		401589 MMP13_HUMAN (4-466): 0: 626: 47.65		JUN_HUMAN (10-155): 1.25e-23: 96.9: 19.73
+	Mm
		404123 MMP13_MOUSE (1-466): 0: 624: 47.89		JUN_MOUSE (10-155): 1.94e-23: 96.5: 19.46
+	Hs
		345302 MMP9_HUMAN (20-206): 1.37e-71: 241: 48.13		FOS_HUMAN (14-158): 2.36e-25: 102: 26.25
+	Hs
		540410 MMP9_HUMAN (20-206): 1.37e-71: 241: 48.13		JUND_HUMAN (53-158): 7.76e-22: 92.2: 24.30
+	Hs
		372975 VTNC_HUMAN (266-437): 4.68e-32: 129: 21.10		JUN_HUMAN (10-155): 1.25e-23: 96.9: 19.73