Interactor 1: PYRF (P03962)
Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) (OMP decarboxylase) (OMPDCase) (OMPdecase) (Uridine 5'-monophosphate synthase) (UMP synthase)
Gene: URA3

Interactor 2: PYRF (P03962)
Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) (OMP decarboxylase) (OMPDCase) (OMPdecase) (Uridine 5'-monophosphate synthase) (UMP synthase)
Gene: URA3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.767

The method score is based on:

Property Details
Experiments 10688190, 19435314
Identification Methods two hybrid, x-ray crystallography
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains OMPdecase~OMPdecase
Common GO terms GO:0004588 - orotate phosphoribosyltransferase activity
GO:0004590 - orotidine-5'-phosphate decarboxylase activity
GO:0005829 - cytosol
GO:0006207 - 'de novo' pyrimidine nucleobase biosynthetic process
GO:0006222 - UMP biosynthetic process
and 1 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 267
Sc

1 267
+ Hs
+ Sp
+ Sp

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Last updated: 15 Jul 2024