Interactor 1: SLPI (P03973)
Antileukoproteinase (ALP) (BLPI) (HUSI-1) (Mucus proteinase inhibitor) (MPI) (Protease inhibitor WAP4) (Secretory leukocyte protease inhibitor) (Seminal proteinase inhibitor) (WAP four-disulfide core domain protein 4)
Gene: SLPI

Interactor 2: ELNE (P08246)
Neutrophil elastase (EC 3.4.21.37) (Bone marrow serine protease) (Elastase-2) (Human leukocyte elastase) (HLE) (Medullasin) (PMN elastase)
Gene: ELANE

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.90 0.614

The method score is based on:

Property Details
Experiments 18421166
Identification Methods x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Trypsin~WAP
Common GO terms GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0032496 - response to lipopolysaccharide
GO:0035580 - specific granule lumen
GO:0062023 - collagen-containing extracellular matrix
and 1 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024