HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: ENOA (P06733)
Alpha-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (C-myc promoter-binding protein) (Enolase 1) (MBP-1) (MPB-1) (Non-neural enolase) (NNE) (Phosphopyruvate hydratase) (Plasminogen-binding protein)
Gene: ENO1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	36244648, 37045861
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 434
+	Hs
		417119 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		ENOA_HUMAN (1-434): 0: 764: 100.00
+	Gg
		337664 SRC_CHICK (331-607): 2.94e-106: 333: 33.45		ENOA_CHICK (1-431): 0: 767: 93.50
+	Hs
		417126 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		ENOA_HUMAN (1-434): 0: 764: 100.00
+	Mm
		403412 SRC_MOUSE (331-607): 3.87e-105: 330: 33.10		ENOA_MOUSE (1-434): 0: 761: 94.70
+	Hs
		411940 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		ENOA_HUMAN (1-434): 0: 764: 100.00
+	Mm
		566042 FYN_MOUSE (342-607): 7.04e-40: 155: 35.29		ENOA_MOUSE (1-434): 0: 761: 94.70