HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: VIGLN (Q00341)
Vigilin (High density lipoprotein-binding protein) (HDL-binding protein)
Gene: HDLBP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	36244648, 37045861
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 1268
+	Hs
		542863 BRAF_HUMAN (39-647): 1.29e-170: 507: 55.88		VIGLN_HUMAN (1-1268): 0: 939: 100.00
+	Hs
		522913 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		VIGLN_HUMAN (1-1268): 0: 939: 100.00
+	Hs
		374695 RAF1_HUMAN (1-648): 0: 652: 100.00		FUBP3_HUMAN (796-1122): 1.09e-33: 140: 16.85
+	Hs
		374639 RAF1_HUMAN (1-648): 0: 652: 100.00		FUBP2_HUMAN (227-575): 5.22e-28: 123: 13.06
+	Hs
		127977 RAF1_HUMAN (1-648): 0: 652: 100.00		IF2B3_HUMAN (23-228): 7.78e-25: 113: 15.70
+	Hs
		374269 RAF1_HUMAN (1-648): 0: 652: 100.00		PCBP2_HUMAN (968-1137): 1.24e-22: 103: 20.57
+	Hs
		374997 RAF1_HUMAN (1-648): 0: 652: 100.00		IF2B1_HUMAN (58-368): 1.59e-20: 99.6: 15.52
+	Hs
		375177 RAF1_HUMAN (1-648): 0: 652: 100.00		IF2B2_HUMAN (920-1124): 2.37e-18: 92.7: 14.76
+	Hs
		374268 RAF1_HUMAN (1-648): 0: 652: 100.00		PCBP1_HUMAN (1128-1232): 3.39e-10: 65.3: 16.19
+	Hs
		488818 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		IF2B1_HUMAN (58-368): 1.59e-20: 99.6: 15.52
+	Hs
		488835 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		IF2B2_HUMAN (920-1124): 2.37e-18: 92.7: 14.76
+	Hs
		522876 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PCBP3_HUMAN (934-1148): 1.25e-24: 109: 18.27
+	Hs
		522998 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PCBP2_HUMAN (968-1137): 1.24e-22: 103: 20.57