HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: CIRBP (Q14011)
Cold-inducible RNA-binding protein (A18 hnRNP) (Glycine-rich RNA-binding protein CIRP)
Gene: CIRBP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36244648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 172
+	Hs
		374855 RAF1_HUMAN (1-648): 0: 652: 100.00		RBM38_HUMAN (5-90): 2.65e-32: 117: 40.70
+	Hs
		374053 RAF1_HUMAN (1-648): 0: 652: 100.00		RBM3_HUMAN (1-166): 4.5e-33: 116: 54.22
+	Hs
		374171 RAF1_HUMAN (1-648): 0: 652: 100.00		PABP4_HUMAN (7-170): 1.39e-28: 112: 20.12
+	Hs
		373604 RAF1_HUMAN (1-648): 0: 652: 100.00		PABP1_HUMAN (7-162): 4.32e-26: 105: 18.59
+	Hs
		373807 RAF1_HUMAN (1-648): 0: 652: 100.00		RBMX_HUMAN (2-86): 3.45e-18: 82: 62.35
+	Hs
		374066 RAF1_HUMAN (1-648): 0: 652: 100.00		TIAR_HUMAN (2-151): 1.75e-16: 77.2: 20.53
+	Hs
		488712 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		CIRBP_HUMAN (1-172): 1.12e-39: 134: 100.00
+	Hs
		488705 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		PABP4_HUMAN (7-170): 1.39e-28: 112: 20.12
+	Hs
		488548 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		PABP1_HUMAN (7-162): 4.32e-26: 105: 18.59
+	Hs
		522960 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP4_HUMAN (7-170): 1.39e-28: 112: 20.12
+	Hs
		523147 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP3_HUMAN (7-169): 9.17e-27: 107: 18.94
+	Hs
		516342 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP1_HUMAN (7-162): 4.32e-26: 105: 18.59