HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: WDR43 (Q15061)
WD repeat-containing protein 43 (U3 small nucleolar RNA-associated protein 5 homolog)
Gene: WDR43

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	36244648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 677
+	Hs
		373991 RAF1_HUMAN (1-648): 0: 652: 100.00		WDR5_HUMAN (157-440): 1.42e-43: 161: 12.11
+	Hs
		373927 RAF1_HUMAN (1-648): 0: 652: 100.00		COPA_HUMAN (161-341): 2.58e-24: 111: 10.93
+	Hs
		375094 RAF1_HUMAN (1-648): 0: 652: 100.00		WDR3_HUMAN (9-463): 1.11e-24: 111: 7.53
+	Hs
		374390 RAF1_HUMAN (1-648): 0: 652: 100.00		Q6FHM2_HUMAN (5-154): 6.06e-19: 90.6: 18.00
+	Hs
		374315 RAF1_HUMAN (1-648): 0: 652: 100.00		SMU1_HUMAN (117-336): 2.99e-15: 81.1: 18.62
+	Hs
		374672 RAF1_HUMAN (1-648): 0: 652: 100.00		SNR40_HUMAN (251-417): 1.07e-13: 74.8: 4.74
+	Hs
		542907 BRAF_HUMAN (39-647): 1.29e-170: 507: 55.88		FBXW7_HUMAN (5-295): 1.2e-60: 217: 16.13
+	Hs
		542841 BRAF_HUMAN (39-647): 1.29e-170: 507: 55.88		COPA_HUMAN (161-341): 2.58e-24: 111: 10.93
+	Mm
		655970 BRAF_MOUSE (38-647): 3.22e-169: 503: 55.52		COPA_MOUSE (161-341): 1.02e-24: 112: 10.93
+	Hs
		488631 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		COPA_HUMAN (161-341): 2.58e-24: 111: 10.93
+	Hs
		412300 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		SNR40_HUMAN (251-417): 1.07e-13: 74.8: 4.74
+	Zm
		38001 A0A1D6NRI5_MAIZE (315-633): 4.57e-40: 159: 30.81		A0A1D6MEH7_MAIZE (198-580): 6.91e-28: 119: 8.06
+	Hs
		1167084 KSR2_HUMAN (332-623): 6.72e-43: 168: 34.43		TBL1R_HUMAN (250-418): 3.33e-11: 68.3: 8.15