HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: THOC6 (Q86W42)
THO complex subunit 6 homolog (Functional spliceosome-associated protein 35) (fSAP35) (WD repeat-containing protein 58)
Gene: THOC6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36244648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006915 - apoptotic process
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 341
+	Hs
		236184 RAF1_HUMAN (1-648): 0: 652: 100.00		PRP17_HUMAN (1-284): 9.1e-50: 176: 8.67
+	Hs
		374672 RAF1_HUMAN (1-648): 0: 652: 100.00		SNR40_HUMAN (1-152): 5.89e-29: 116: 14.65
+	Hs
		374012 RAF1_HUMAN (1-648): 0: 652: 100.00		GBB1_HUMAN (117-339): 5.07e-23: 99.7: 12.04
+	Hs
		374566 RAF1_HUMAN (1-648): 0: 652: 100.00		WDR36_HUMAN (18-259): 8.21e-18: 86.4: 17.00
+	Hs
		373991 RAF1_HUMAN (1-648): 0: 652: 100.00		WDR5_HUMAN (1-103): 1.25e-14: 75.4: 13.76
+	Hs
		542907 BRAF_HUMAN (39-647): 1.29e-170: 507: 55.88		FBXW7_HUMAN (1-149): 4.03e-22: 99.3: 7.38
+	Hs
		488745 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		A16L1_HUMAN (65-330): 1.22e-16: 82.9: 15.39
+	Mm
		384064 ARAF_MOUSE (45-646): 4.46e-168: 495: 58.65		A16L1_MOUSE (13-330): 1.42e-15: 79.4: 16.31
+	Hs
		412300 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		SNR40_HUMAN (1-152): 5.89e-29: 116: 14.65
+	Hs
		412122 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		GBB1_HUMAN (117-339): 5.07e-23: 99.7: 12.04
+	Hs
		433423 YES_HUMAN (329-607): 1.22e-105: 332: 33.92		WDR36_HUMAN (18-259): 8.21e-18: 86.4: 17.00
+	Hs
		433385 YES_HUMAN (329-607): 1.22e-105: 332: 33.92		A16L1_HUMAN (65-330): 1.22e-16: 82.9: 15.39
+	Hs
		412229 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		A16L1_HUMAN (65-330): 1.22e-16: 82.9: 15.39
+	Hs
		1167084 KSR2_HUMAN (332-623): 6.72e-43: 168: 34.43		TBL1R_HUMAN (205-336): 4.01e-12: 69: 10.60
+	Zm
		38001 A0A1D6NRI5_MAIZE (315-633): 4.57e-40: 159: 30.81		A0A1D6MEH7_MAIZE (243-338): 6.01e-13: 71.2: 10.24