HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: RAB43 (Q86YS6)
Ras-related protein Rab-43 (Ras-related protein Rab-41)
Gene: RAB43

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36244648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C1_1~Ras, Pkinase~Ras, RBD~Ras
Common GO terms	GO:0005794 - Golgi apparatus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 212
+	Hs
		374007 RAF1_HUMAN (1-648): 0: 652: 100.00		RAB1A_HUMAN (9-212): 8.23e-87: 256: 42.93
+	Hs
		374854 RAF1_HUMAN (1-648): 0: 652: 100.00		RAB1B_HUMAN (11-212): 7.6e-87: 256: 44.55
+	Hs
		59810 RAF1_HUMAN (1-648): 0: 652: 100.00		RAB19_HUMAN (12-204): 1.21e-81: 243: 56.48
+	Hs
		373973 RAF1_HUMAN (1-648): 0: 652: 100.00		RAB8A_HUMAN (11-212): 3.93e-79: 237: 42.44
+	Hs
		374003 RAF1_HUMAN (1-648): 0: 652: 100.00		RB11A_HUMAN (9-211): 3.2e-79: 237: 42.06
+	Hs
		542851 BRAF_HUMAN (39-647): 1.29e-170: 507: 55.88		RAB1A_HUMAN (9-212): 8.23e-87: 256: 42.93
+	Hs
		488650 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		RB11A_HUMAN (9-211): 3.2e-79: 237: 42.06
+	Hs
		522882 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		RB11A_HUMAN (9-211): 3.2e-79: 237: 42.06
+	Hs
		523004 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		RB11B_HUMAN (9-211): 3.57e-79: 237: 40.74
+	Hs
		433312 YES_HUMAN (329-607): 1.22e-105: 332: 33.92		RB11A_HUMAN (9-211): 3.2e-79: 237: 42.06