Protein: EFNB3
Ephrin-B3 (EPH-related receptor transmembrane ligand ELK-L3) (EPH-related receptor tyrosine kinase ligand 8) (LERK-8)

Gene: EFNB3
Organism: Homo sapiens
Interactions: 61
UniProt ID: Q15768

Gene Ontology (top 5):
GO:0001618 - virus receptor activity
GO:0005005 - transmembrane-ephrin receptor activity
GO:0005886 - plasma membrane
GO:0007267 - cell-cell signaling
GO:0007399 - nervous system development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

932078

EPHA4
Ephrin type-A receptor 4

4

20

Small-scale

0.902

High

627530

DPA1
HLA class II histocompatibility antigen, DP alpha 1 chain

3

3

High-throughput

0.667

High

890655

RGS3
Regulator of G-protein signaling 3

3

4

High-throughput

0.662

High

1153468

MPP7
MAGUK p55 subfamily member 7

3

3

High-throughput

0.662

High

931810

EPHB3
Ephrin type-B receptor 3

1

20

Small-scale

0.647

High

65346

TCAF2
TRPM8 channel-associated factor 2

2

1

High-throughput

0.628

High

749333

TNFL8
Tumor necrosis factor ligand superfamily member 8

2

1

High-throughput

0.628

High

1091504

DLG1
Disks large homolog 1

2

3

High-throughput

0.628

High

1108550

TBB3
Tubulin beta-3 chain

2

15

High-throughput

0.628

High

1153473

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

2

1

High-throughput

0.628

High

1153476

IGSF8
Immunoglobulin superfamily member 8

2

1

High-throughput

0.628

High

1153475

TB22A
TBC1 domain family member 22A

3

2

High-throughput

0.609

High

375551

RASK
GTPase KRas

2

14

High-throughput

0.584

High

1153466

TBB8
Tubulin beta-8 chain

2

15

High-throughput

0.574

High

1153469

PKN3
Serine/threonine-protein kinase N3

2

3

High-throughput

0.574

High

1153472

DEN6A
Protein DENND6A

2

2

High-throughput

0.574

High

1153477

EVI5L
EVI5-like protein

2

2

High-throughput

0.574

High

1153490

RTEL1
Regulator of telomere elongation helicase 1

2

2

High-throughput

0.574

High

848490

MAGA8
Melanoma-associated antigen 8

2

1

High-throughput

0.549

High

990261

1433Z
14-3-3 protein zeta/delta

1

1

High-throughput

0.541

High

761230

RYK
Tyrosine-protein kinase RYK

1

12

High-throughput

0.536

High

1112362

MTMR1
Phosphatidylinositol-3-phosphate phosphatase MTMR1

1

5

High-throughput

0.536

High

1153486

PICK1
PRKCA-binding protein

1

2

High-throughput

0.536

High

1153492

CLC4A
C-type lectin domain family 4 member A

1

1

High-throughput

0.536

High

1153480

P2RX7
P2X purinoceptor 7

1

0

High-throughput

0.518

High

480799

LEG1
Galectin-1

1

0

High-throughput

0.513

High

1153491

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.513

High

1008065

RELN
Reelin

1

4

Small-scale

0.501

High

1153487

RHBL2
Rhomboid-related protein 2

1

2

Small-scale

0.501

High

1153488

AATF
Protein AATF

1

1

High-throughput

0.494

High

996964

TBA4A
Tubulin alpha-4A chain

1

11

High-throughput

0.489

High

997356

TBB4B
Tubulin beta-4B chain

1

15

High-throughput

0.489

High

1153471

UBP30
Ubiquitin carboxyl-terminal hydrolase 30

1

2

High-throughput

0.489

High

1153478

MTMR8
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR8

1

5

High-throughput

0.489

High

1153484

F234A
Protein FAM234A

1

1

High-throughput

0.489

High

373944

RASN
GTPase NRas

1

14

High-throughput

0.479

High

374619

RASH
GTPase HRas

1

10

High-throughput

0.479

High

1153465

MICB
MHC class I polypeptide-related sequence B

1

0

High-throughput

0.426

High

1153485

KC1G1
Casein kinase I isoform gamma-1

1

0

High-throughput

0.426

High

335685

MOCS3
Adenylyltransferase and sulfurtransferase MOCS3

1

1

High-throughput

0.407

High

457463

TBB5
Tubulin beta chain

1

15

High-throughput

0.407

High

472763

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

3

High-throughput

0.407

High

1153470

BRID5
BRICHOS domain-containing protein 5

1

1

High-throughput

0.407

High

62213

DEN11
DENN domain-containing protein 11

3

0

High-throughput

0.345

High

64455

F221B
Protein FAM221B

2

0

High-throughput

0.328

High

219077

RA51C
DNA repair protein RAD51 homolog 3

2

0

High-throughput

0.328

High

571441

GLU2B
Glucosidase 2 subunit beta

2

0

High-throughput

0.328

High

1153479

TRI11
E3 ubiquitin-protein ligase TRIM11

2

0

High-throughput

0.328

High

1153493

CDYL
Chromodomain Y-like protein

2

0

High-throughput

0.328

High

1147035

ELOC
Elongin-C

1

0

High-throughput

0.282

High

600612

NAGAB
Alpha-N-acetylgalactosaminidase

1

0

High-throughput

0.279

Low

692703

CALL3
Calmodulin-like protein 3

1

0

High-throughput

0.279

Low

1153467

NHLC3
NHL repeat-containing protein 3

1

0

High-throughput

0.279

Low

1153481

FUCO2
Plasma alpha-L-fucosidase

1

0

High-throughput

0.279

Low

1153482

THUM3
tRNA

1

0

High-throughput

0.279

Low

442726

RB
Retinoblastoma-associated protein

1

0

High-throughput

0.232

Low

749610

ACSL1
Long-chain-fatty-acid--CoA ligase 1

1

0

High-throughput

0.232

Low

833629

NAA10
N-alpha-acetyltransferase 10

1

0

High-throughput

0.232

Low

1153474

SPX3
Sugar phosphate exchanger 3

1

0

High-throughput

0.232

Low

1153483

CHIA
Acidic mammalian chitinase

1

0

High-throughput

0.232

Low

1153489

UTP6
U3 small nucleolar RNA-associated protein 6 homolog

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025