HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: TRI47 (Q96LD4)
E3 ubiquitin-protein ligase TRIM47 (EC 2.3.2.27) (Gene overexpressed in astrocytoma protein) (RING finger protein 100) (Tripartite motif-containing protein 47)
Gene: TRIM47

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38496616
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 638
+	Hs
		374227 RAF1_HUMAN (1-648): 0: 652: 100.00		TRI25_HUMAN (3-625): 7.09e-101: 322: 23.79
+	Hs
		374216 RAF1_HUMAN (1-648): 0: 652: 100.00		TRI14_HUMAN (179-580): 7.08e-72: 240: 23.67
+	Hs
		374788 RAF1_HUMAN (1-648): 0: 652: 100.00		TRI56_HUMAN (7-422): 1.5e-67: 236: 24.08
+	Hs
		373660 RAF1_HUMAN (1-648): 0: 652: 100.00		RO52_HUMAN (5-290): 5.68e-19: 92.4: 16.78
+	Hs
		412363 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		TRI39_HUMAN (87-588): 5.02e-120: 368: 16.90
+	Hs
		522983 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		TRI25_HUMAN (3-625): 7.09e-101: 322: 23.79
+	Hs
		523138 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		TRIM7_HUMAN (87-626): 1.04e-100: 318: 18.56
+	Hs
		488570 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		RO52_HUMAN (5-290): 5.68e-19: 92.4: 16.78
+	Hs
		523137 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		TRI15_HUMAN (129-563): 1.94e-47: 175: 15.84
+	Hs
		433465 YES_HUMAN (329-607): 1.22e-105: 332: 33.92		TRIM5_HUMAN (1-254): 2.41e-19: 93.6: 16.41
+	Hs
		411977 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		TRI27_HUMAN (3-398): 6.85e-19: 92.4: 12.66
+	Hs
		523048 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		TRI50_HUMAN (3-115): 8.86e-15: 79.3: 24.78