HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: SRSF8 (Q9BRL6)
Serine/arginine-rich splicing factor 8 (Pre-mRNA-splicing factor SRP46) (Splicing factor SRp46) (Splicing factor, arginine/serine-rich 2B)
Gene: SRSF8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36244648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 282
+	Hs
		374067 RAF1_HUMAN (1-648): 0: 652: 100.00		SRSF2_HUMAN (1-100): 1.3e-41: 144: 80.00
+	Hs
		374855 RAF1_HUMAN (1-648): 0: 652: 100.00		RBM38_HUMAN (14-191): 6.85e-31: 117: 21.35
+	Hs
		374171 RAF1_HUMAN (1-648): 0: 652: 100.00		PABP4_HUMAN (2-103): 9.14e-22: 96.7: 19.61
+	Hs
		373604 RAF1_HUMAN (1-648): 0: 652: 100.00		PABP1_HUMAN (2-103): 1.99e-20: 92.9: 18.63
+	Hs
		374066 RAF1_HUMAN (1-648): 0: 652: 100.00		TIAR_HUMAN (8-102): 5.22e-19: 87.5: 26.32
+	Hs
		374212 RAF1_HUMAN (1-648): 0: 652: 100.00		CIRBP_HUMAN (16-160): 2.29e-19: 85: 33.79
+	Hs
		488705 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		PABP4_HUMAN (2-103): 9.14e-22: 96.7: 19.61
+	Hs
		488548 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		PABP1_HUMAN (2-103): 1.99e-20: 92.9: 18.63
+	Hs
		488712 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		CIRBP_HUMAN (16-160): 2.29e-19: 85: 33.79
+	Hs
		522960 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP4_HUMAN (2-103): 9.14e-22: 96.7: 19.61
+	Hs
		516342 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP1_HUMAN (2-103): 1.99e-20: 92.9: 18.63
+	Hs
		523147 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP3_HUMAN (2-103): 2.88e-19: 89.4: 19.61