HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: FKBPL (Q9UIM3)
FK506-binding protein-like (WAF-1/CIP1 stabilizing protein 39) (WISp39)
Gene: FKBPL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25036637
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 349
+	Hs
		374083 RAF1_HUMAN (1-648): 0: 652: 100.00		FKBP4_HUMAN (83-348): 7.15e-59: 198: 26.30
+	Hs
		374182 RAF1_HUMAN (1-648): 0: 652: 100.00		FKBP5_HUMAN (83-348): 5.51e-57: 193: 23.53
+	Hs
		374114 RAF1_HUMAN (1-648): 0: 652: 100.00		PPID_HUMAN (78-349): 1.59e-50: 174: 21.45
+	Hs
		374861 RAF1_HUMAN (1-648): 0: 652: 100.00		UN45A_HUMAN (208-348): 2.18e-36: 141: 33.33
+	Hs
		542932 BRAF_HUMAN (39-647): 1.29e-170: 507: 55.88		FKBPL_HUMAN (1-349): 1.14e-87: 269: 100.00
+	Hs
		374290 RAF1_HUMAN (1-648): 0: 652: 100.00		TOM34_HUMAN (207-333): 6.68e-25: 104: 28.35
+	Hs
		373773 RAF1_HUMAN (1-648): 0: 652: 100.00		STIP1_HUMAN (207-337): 8.63e-21: 95.3: 20.61
+	Hs
		374106 RAF1_HUMAN (1-648): 0: 652: 100.00		SPAG1_HUMAN (203-340): 3.25e-20: 94: 29.71
+	Gg
		982843 BRAF_CHICK (38-647): 1.98e-169: 504: 56.96		Q646T7_CHICK (83-349): 3.65e-59: 198: 24.14
+	Hs
		542876 BRAF_HUMAN (39-647): 1.29e-170: 507: 55.88		FKBP5_HUMAN (83-348): 5.51e-57: 193: 23.53
+	Hs
		488688 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		FKBP4_HUMAN (83-348): 7.15e-59: 198: 26.30
+	Hs
		488708 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		FKBP5_HUMAN (83-348): 5.51e-57: 193: 23.53
+	Hs
		488716 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		FKBP8_HUMAN (96-349): 1.94e-41: 151: 24.37
+	Hs
		1034905 KSR2_HUMAN (332-623): 6.72e-43: 168: 34.43		FKBP5_HUMAN (83-348): 5.51e-57: 193: 23.53
+	Hs
		259949 KSR2_HUMAN (332-623): 6.72e-43: 168: 34.43		FKBP6_HUMAN (73-349): 1.03e-41: 150: 21.22
+	Hs
		1167086 KSR2_HUMAN (332-623): 6.72e-43: 168: 34.43		RPAP3_HUMAN (206-337): 2.43e-27: 114: 26.52