Protein: ROBO2
Roundabout homolog 2

Gene: ROBO2
Organism: Homo sapiens
Interactions: 43
UniProt ID: Q9HCK4

Gene Ontology (top 5):
GO:0001656 - metanephros development
GO:0001657 - ureteric bud development
GO:0003129 - heart induction
GO:0003148 - outflow tract septum morphogenesis
GO:0003180 - aortic valve morphogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1418676

PAR6B
Partitioning defective 6 homolog beta

1

1

High-throughput

0.691

High

409613

DPB1
HLA class II histocompatibility antigen, DP beta 1 chain

1

2

High-throughput

0.656

High

287732

KS6A5
Ribosomal protein S6 kinase alpha-5

1

0

High-throughput

0.622

High

375974

RASK
GTPase KRas

1

14

High-throughput

0.618

High

463779

LYN
Tyrosine-protein kinase Lyn

1

9

High-throughput

0.618

High

710503

EPHA2
Ephrin type-A receptor 2

1

11

High-throughput

0.618

High

978319

RHOB
Rho-related GTP-binding protein RhoB

1

12

High-throughput

0.618

High

1420062

KPCD2
Serine/threonine-protein kinase D2

1

1

High-throughput

0.618

High

1439191

ROBO2
Roundabout homolog 2

1

16

Small-scale

0.618

High

1439197

ALK
ALK tyrosine kinase receptor

1

14

High-throughput

0.618

High

1439198

ROBO1
Roundabout homolog 1

1

17

Small-scale

0.618

High

1351705

GP152
Probable G-protein coupled receptor 152

2

3

High-throughput

0.606

High

652583

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

5

High-throughput

0.587

High

933958

NR1H2
Oxysterols receptor LXR-beta

1

4

High-throughput

0.587

High

1400552

TM237
Transmembrane protein 237

2

0

High-throughput

0.580

High

1255631

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.553

High

1439192

UBQL4
Ubiquilin-4

1

0

High-throughput

0.549

High

1096932

FADD
FAS-associated death domain protein

1

5

High-throughput

0.536

High

599134

CBPE
Carboxypeptidase E

1

0

High-throughput

0.518

High

1439194

VAPA
Vesicle-associated membrane protein-associated protein A

1

0

High-throughput

0.513

High

122855

KIF2A
Kinesin-like protein KIF2A

1

2

High-throughput

0.489

High

230572

KIF1C
Kinesin-like protein KIF1C

1

3

High-throughput

0.489

High

373205

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.489

High

566048

EF2
Elongation factor 2

1

2

High-throughput

0.479

High

604221

CXA1
Gap junction alpha-1 protein

1

5

High-throughput

0.479

High

1041305

CAV1
Caveolin-1

1

2

High-throughput

0.479

High

1159859

OCLN
Occludin

1

2

High-throughput

0.479

High

530402

TAU
Microtubule-associated protein tau

1

7

High-throughput

0.445

High

1119313

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

6

High-throughput

0.445

High

1323767

S39AB
Zinc transporter ZIP11

1

5

High-throughput

0.445

High

258338

TRI13
E3 ubiquitin-protein ligase TRIM13

1

2

High-throughput

0.439

High

106681

APRIO
Alternative prion protein

1

8

High-throughput

0.437

High

1439195

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

2

High-throughput

0.437

High

1327856

KCNRG
Potassium channel regulatory protein

1

7

High-throughput

0.417

High

1287889

MTA70
N(6)-adenosine-methyltransferase catalytic subunit METTL3

1

0

High-throughput

0.279

Low

1439193

TM248
Transmembrane protein 248

1

0

High-throughput

0.279

Low

239395

BNI3L
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

1

0

High-throughput

0.265

Low

1259029

CENPU
Centromere protein U

1

0

High-throughput

0.265

Low

1349376

RDH11
Retinol dehydrogenase 11

1

0

High-throughput

0.265

Low

350742

NOE2
Noelin-2

1

0

High-throughput

0.238

Low

1065441

SSRP1
FACT complex subunit SSRP1

1

0

High-throughput

0.238

Low

1439196

PPR1B
Protein phosphatase 1 regulatory subunit 1B

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025