HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: SF3B6 (Q9Y3B4)
Splicing factor 3B subunit 6 (Pre-mRNA branch site protein p14) (SF3b 14 kDa subunit) (SF3B14a) (Spliceosome-associated protein, 14-kDa) (Splicing factor 3b, subunit 6, 14kDa)
Gene: SF3B6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36244648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 125
+	Hs
		373552 RAF1_HUMAN (1-648): 0: 652: 100.00		RU2B_HUMAN (16-111): 5.15e-38: 129: 25.00
+	Hs
		374171 RAF1_HUMAN (1-648): 0: 652: 100.00		PABP4_HUMAN (12-99): 1.35e-22: 93.3: 22.47
+	Hs
		373604 RAF1_HUMAN (1-648): 0: 652: 100.00		PABP1_HUMAN (20-99): 4.52e-21: 89.1: 23.46
+	Hs
		374108 RAF1_HUMAN (1-648): 0: 652: 100.00		SRSF1_HUMAN (21-91): 3.36e-18: 79: 33.80
+	Hs
		374164 RAF1_HUMAN (1-648): 0: 652: 100.00		SRSF9_HUMAN (21-94): 4.86e-17: 75.1: 31.08
+	Hs
		488705 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		PABP4_HUMAN (12-99): 1.35e-22: 93.3: 22.47
+	Hs
		488548 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		PABP1_HUMAN (20-99): 4.52e-21: 89.1: 23.46
+	Hs
		522960 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP4_HUMAN (12-99): 1.35e-22: 93.3: 22.47
+	Hs
		523147 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP3_HUMAN (20-99): 3.04e-21: 89.5: 23.46
+	Hs
		516342 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP1_HUMAN (20-99): 4.52e-21: 89.1: 23.46