HitPredict

Interactor 1: RPB1 (P04050)
DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit 1) (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase III largest subunit) (RNA polymerase II subunit B220)
Gene: RPO21

Interactor 2: RPB3 (P16370)
DNA-directed RNA polymerase II subunit RPB3 (RNA polymerase II subunit 3) (RNA polymerase II subunit B3) (B44.5) (DNA-directed RNA polymerase II 45 kDa polypeptide)
Gene: RPB3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.993

The method score is based on:

Property Details
Experiments 20637414, 12242279, 10984524, 14536083, 16076843, 15610738, 10024884, 16554755, 16301539, 26787877, 29220656, 33226341, 37968396, 20494970, 14759368, 23836886, 23748379, 23459708, 25416796, 24035501 and 19 others

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Identification Methods pull down, affinity chromatography technology, x-ray crystallography, biochemical, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_L~RNA_pol_Rpb1_2, RNA_pol_L~RNA_pol_Rpb1_3, RNA_pol_L~RNA_pol_Rpb1_4, RNA_pol_L~RNA_pol_Rpb1_5
Common GO terms GO:0001055 - RNA polymerase II activity
GO:0001172 - RNA-templated transcription
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005665 - RNA polymerase II, core complex
and 4 others

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Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1733
Sc

1 318
+ Sp
+ Sc
+ Hs
+ Hs
+ Sc
+ Hv
+ Sc
+ Hs
+ At
+ At
+ At
+ Hs
+ At
+ Hs
+ Hv
+ Bt
+ Sc
+ Hs

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Last updated: 15 Jul 2024