Interactor 1: RPB1 (P04050)
DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit 1) (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase III largest subunit) (RNA polymerase II subunit B220)
Gene: RPO21

Interactor 2: RPAB3 (P20436)
DNA-directed RNA polymerases I, II, and III subunit RPABC3 (RNA polymerases I, II, and III subunit ABC3) (ABC14.4) (ABC14.5) (DNA-directed RNA polymerases I, II, and III 14.5 kDa polypeptide)
Gene: RPB8

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.975

The method score is based on:

Property Details
Experiments 10784442, 11486042, 25315781, 19394294, 21048197, 20720002, 10984524, 15610738, 16301539, 26787877, 33226341, 37968396, 20494970
Identification Methods x-ray crystallography, two hybrid, affinity chromatography technology, biochemical
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rpb1_3~RNA_pol_Rpb8, RNA_pol_Rpb1_4~RNA_pol_Rpb8, RNA_pol_Rpb1_5~RNA_pol_Rpb8
Common GO terms GO:0001055 - RNA polymerase II activity
GO:0001172 - RNA-templated transcription
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005665 - RNA polymerase II, core complex
and 3 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 1733
Sc

1 146
+ Sp
+ Sc
+ Hs
+ Sc
+ At
+ At
+ Hs
+ Hs
+ Hs
+ Bt

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024