HitPredict

Interactor 1: RPB1 (P04050)
DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit 1) (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase III largest subunit) (RNA polymerase II subunit B220)
Gene: RPO21

Interactor 2: T2EA (P36100)
Transcription initiation factor IIE subunit alpha (TFIIE-alpha) (Factor A 66 kDa subunit) (Transcription factor A large subunit)
Gene: TFA1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.834

The method score is based on:

Property Details
Experiments 17632521, 22751016, 24813444
Identification Methods cross-linking study, pull down, affinity chromatography technology
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rpb1_1~TFIIE_alpha
Common GO terms GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0006366 - transcription by RNA polymerase II
GO:0006367 - transcription initiation at RNA polymerase II promoter
GO:0046872 - metal ion binding
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1733
Sc

1 482
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024