Protein: RALA
Ras-related protein Ral-A (EC 3.6.5.2)

Gene: RALA
Organism: Homo sapiens
Interactions: 129
UniProt ID: P11233

Gene Ontology (top 5):
GO:0001843 - neural tube closure
GO:0003924 - GTPase activity
GO:0003925 - G protein activity
GO:0005525 - GTP binding
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

539809

RBP1
RalA-binding protein 1

8

20

Small-scale

0.965

High

539838

EXOC2
Exocyst complex component 2

5

9

Small-scale

0.906

High

374365

RASH
GTPase HRas

3

18

Small-scale

0.834

High

539764

RALB
Ras-related protein Ral-B

3

20

High-throughput

0.827

High

539800

PLD1
Phospholipase D1

2

5

Small-scale

0.778

High

375124

RASK
GTPase KRas

2

19

High-throughput

0.754

High

539817

AN13D
Ankyrin repeat domain-containing protein 13D

1

15

High-throughput

0.691

High

539821

AN13A
Ankyrin repeat domain-containing protein 13A

1

10

High-throughput

0.691

High

539846

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.691

High

539785

PLCD1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1

1

20

Small-scale

0.680

High

539847

ANLN
Anillin

2

8

High-throughput

0.675

High

182036

RGL2
Ral guanine nucleotide dissociation stimulator-like 2

1

20

Small-scale

0.656

High

539814

RGPS1
Ras-specific guanine nucleotide-releasing factor RalGPS1

1

20

Small-scale

0.647

High

539822

RGDSR
Ral-GDS-related protein

1

20

Small-scale

0.647

High

539855

GLSL
Glutaminase liver isoform, mitochondrial

1

20

Small-scale

0.647

High

539841

RAB34
Ras-related protein Rab-34

1

16

Small-scale

0.621

High

539823

RYBP
RING1 and YY1-binding protein

1

7

High-throughput

0.618

High

373747

RASN
GTPase NRas

1

20

High-throughput

0.618

High

400195

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

20

High-throughput

0.618

High

411257

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.618

High

466084

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.618

High

539763

RALA
Ras-related protein Ral-A

1

18

High-throughput

0.618

High

539781

MUC18
Cell surface glycoprotein MUC18

1

20

High-throughput

0.618

High

539784

TSC2
Tuberin

1

13

Small-scale

0.618

High

539788

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.618

High

539791

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

539794

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.618

High

539795

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

2

Small-scale

0.618

High

539797

CDK18
Cyclin-dependent kinase 18

1

15

High-throughput

0.618

High

539833

CNKR2
Connector enhancer of kinase suppressor of ras 2

1

20

Small-scale

0.618

High

539844

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.618

High

539845

PKHA2
Pleckstrin homology domain-containing family A member 2

1

20

Small-scale

0.618

High

539852

DJB11
DnaJ homolog subfamily B member 11

1

5

High-throughput

0.595

High

539793

ARF6
ADP-ribosylation factor 6

2

18

Small-scale

0.584

High

539772

FLNA
Filamin-A

1

9

Small-scale

0.561

High

539816

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.553

High

539853

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.553

High

539830

UBP33
Ubiquitin carboxyl-terminal hydrolase 33

1

11

Small-scale

0.552

High

415303

HSPB1
Heat shock protein beta-1

1

1

High-throughput

0.541

High

123572

MYO1C
Unconventional myosin-Ic

1

17

High-throughput

0.536

High

125821

AP4M1
AP-4 complex subunit mu-1

1

7

High-throughput

0.536

High

269734

CAPON
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

1

15

High-throughput

0.536

High

276885

VPS4B
Vacuolar protein sorting-associated protein 4B

1

8

High-throughput

0.536

High

278001

FLNB
Filamin-B

1

9

High-throughput

0.536

High

292529

RENR
Renin receptor

1

6

High-throughput

0.536

High

539771

ATP5J
ATP synthase peripheral stalk subunit F6, mitochondrial

1

1

High-throughput

0.536

High

539776

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

1

12

Small-scale

0.536

High

539786

MOT1
Monocarboxylate transporter 1

1

16

High-throughput

0.536

High

539812

CEP55
Centrosomal protein of 55 kDa

1

1

High-throughput

0.536

High

539854

LIMA1
LIM domain and actin-binding protein 1

1

20

High-throughput

0.536

High

539857

SMC3
Structural maintenance of chromosomes protein 3

1

1

High-throughput

0.515

High

217245

ARK72
Aflatoxin B1 aldehyde reductase member 2

1

0

High-throughput

0.513

High

539774

ALAT1
Alanine aminotransferase 1

1

0

High-throughput

0.513

High

539818

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

539796

ARF1
ADP-ribosylation factor 1

1

18

Small-scale

0.501

High

539831

HASP
Serine/threonine-protein kinase haspin

1

1

High-throughput

0.489

High

539779

SYUA
Alpha-synuclein

1

5

High-throughput

0.481

High

539819

EXOC8
Exocyst complex component 8

1

3

Small-scale

0.481

High

125181

LEG9
Galectin-9

1

11

High-throughput

0.479

High

178165

NPC1
NPC intracellular cholesterol transporter 1

1

5

High-throughput

0.479

High

240591

PRKN
E3 ubiquitin-protein ligase parkin

1

10

High-throughput

0.479

High

252815

EXOC3
Exocyst complex component 3

1

4

Small-scale

0.479

High

371023

MYC
Myc proto-oncogene protein

1

10

High-throughput

0.479

High

532313

CH60
60 kDa heat shock protein, mitochondrial

1

5

High-throughput

0.479

High

539765

LAMP2
Lysosome-associated membrane glycoprotein 2

1

16

High-throughput

0.479

High

539767

PDIA4
Protein disulfide-isomerase A4

1

1

High-throughput

0.479

High

539768

HLAE
HLA class I histocompatibility antigen, alpha chain E

1

11

High-throughput

0.479

High

539769

RFA2
Replication protein A 32 kDa subunit

1

10

High-throughput

0.479

High

539773

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

3

High-throughput

0.479

High

539787

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

2

High-throughput

0.479

High

539789

CXCR4
C-X-C chemokine receptor type 4

1

6

High-throughput

0.479

High

539790

ABCE1
ATP-binding cassette sub-family E member 1

1

5

High-throughput

0.479

High

539804

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

7

High-throughput

0.479

High

539807

CUL7
Cullin-7

1

2

High-throughput

0.479

High

539808

KIF14
Kinesin-like protein KIF14

1

13

High-throughput

0.479

High

539824

EMC5
ER membrane protein complex subunit 5

1

6

High-throughput

0.479

High

539825

S2541
Mitochondrial carrier protein SCaMC-3L

1

6

High-throughput

0.479

High

539827

AMER2
APC membrane recruitment protein 2

1

13

High-throughput

0.479

High

539834

ESR2
Estrogen receptor beta

1

15

High-throughput

0.479

High

539835

EXOC4
Exocyst complex component 4

1

5

Small-scale

0.479

High

539843

CCDC8
Coiled-coil domain-containing protein 8

1

5

High-throughput

0.479

High

539849

RCC2
Protein RCC2

1

1

Small-scale

0.479

High

539851

HDAC6
Protein deacetylase HDAC6

1

9

High-throughput

0.479

High

539856

UBQL1
Ubiquilin-1

1

11

High-throughput

0.479

High

539859

MD1L1
Mitotic spindle assembly checkpoint protein MAD1

1

19

High-throughput

0.479

High

284738

RMXL2
RNA-binding motif protein, X-linked-like-2

1

4

High-throughput

0.470

High

539836

ZBT10
Zinc finger and BTB domain-containing protein 10

1

5

High-throughput

0.470

High

539782

CTCF
Transcriptional repressor CTCF

1

3

Small-scale

0.464

High

539801

SMAD4
Mothers against decapentaplegic homolog 4

1

2

High-throughput

0.464

High

254770

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

4

High-throughput

0.445

High

404638

PRIO
Major prion protein

1

1

High-throughput

0.445

High

516304

CALM1
Calmodulin-1

1

5

High-throughput

0.445

High

516377

CALM2
Calmodulin-2

1

5

High-throughput

0.445

High

516459

CALM3
Calmodulin-3

1

5

High-throughput

0.445

High

528949

TAU
Microtubule-associated protein tau

1

19

High-throughput

0.445

High

539766

CFTR
Cystic fibrosis transmembrane conductance regulator

1

17

High-throughput

0.445

High

539780

CNDD3
Condensin-2 complex subunit D3

1

3

High-throughput

0.445

High

539799

TRDN
Triadin

1

8

High-throughput

0.445

High

539803

CUL3
Cullin-3

1

8

High-throughput

0.445

High

539805

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

7

High-throughput

0.445

High

539840

ZNT3
Probable proton-coupled zinc antiporter SLC30A3

1

20

High-throughput

0.445

High

539842

ZDHC5
Palmitoyltransferase ZDHHC5

1

20

High-throughput

0.445

High

539832

PIHD2
PIH1 domain-containing protein 2

1

2

Small-scale

0.439

High

539858

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

1

Small-scale

0.439

High

105203

APRIO
Alternative prion protein

1

5

High-throughput

0.437

High

293116

CD123
Translation initiation factor eIF2 assembly protein

1

9

High-throughput

0.437

High

539770

CEBPB
CCAAT/enhancer-binding protein beta

1

6

High-throughput

0.437

High

539775

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

11

High-throughput

0.437

High

539778

RFA3
Replication protein A 14 kDa subunit

1

8

High-throughput

0.437

High

539783

TSP3
Thrombospondin-3

1

15

High-throughput

0.437

High

539792

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.437

High

539802

BIRC3
Baculoviral IAP repeat-containing protein 3

1

9

High-throughput

0.437

High

539811

MIDN
Midnolin

1

4

High-throughput

0.437

High

539813

IF44L
Interferon-induced protein 44-like

1

1

High-throughput

0.437

High

539815

TSBP1
Testis-expressed basic protein 1

1

8

High-throughput

0.437

High

539826

EMC1
ER membrane protein complex subunit 1

1

3

High-throughput

0.437

High

539829

IFI44
Interferon-induced protein 44

1

1

High-throughput

0.437

High

539850

RRBP1
Ribosome-binding protein 1

1

15

High-throughput

0.437

High

539837

SAAL1
Protein SAAL1

1

2

High-throughput

0.407

High

539839

ZBT18
Zinc finger and BTB domain-containing protein 18

1

2

High-throughput

0.407

High

539777

MCM5
DNA replication licensing factor MCM5

1

0

High-throughput

0.279

Low

539810

ZNHI3
Zinc finger HIT domain-containing protein 3

1

0

High-throughput

0.279

Low

539820

K2013
Uncharacterized protein KIAA2013

1

0

High-throughput

0.279

Low

539828

FBH1
F-box DNA helicase 1

1

0

High-throughput

0.279

Low

539848

INT7
Integrator complex subunit 7

1

0

High-throughput

0.279

Low

318930

DEND
Dendrin

1

0

High-throughput

0.269

Low

539798

SIA4C
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4

1

0

High-throughput

0.249

Low

539806

TFDP2
Transcription factor Dp-2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025