HitPredict

Interactor 1: RPB1 (P04050)
DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit 1) (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase III largest subunit) (RNA polymerase II subunit B220)
Gene: RPO21

Interactor 2: RUVB2 (Q12464)
RuvB-like protein 2 (RUVBL2) (EC 3.6.4.12) (TIP49-homology protein 2) (TIP49b homolog)
Gene: RVB2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.692

Property	Details
Experiments	26831523, 25340856, 23438601, 33226341
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1733 Sc			1 471
+	Sc
		375494 RPB1_YEAST (1-1555): 0: 1770: 100.00		RUVB1_YEAST (8-448): 0: 624: 41.10
+	Hs
		156082 RPC1_HUMAN (1-1457): 0: 1366: 31.97		RUVB2_HUMAN (4-451): 0: 680: 68.15
+	Mm
		70955 B2RXC6_MOUSE (1-1454): 0: 1372: 32.04		RUVB1_MOUSE (10-448): 0: 658: 41.72
+	Hs
		156083 RPC1_HUMAN (1-1457): 0: 1366: 31.97		RUVB1_HUMAN (10-448): 0: 658: 41.72
+	Hs
		317187 RPA1_HUMAN (912-1446): 2.52e-35: 150: 14.81		RUVB2_HUMAN (4-451): 0: 680: 68.15
+	Mm
		192267 RPA1_MOUSE (911-1446): 4.76e-36: 152: 15.16		RUVB1_MOUSE (10-448): 0: 658: 41.72
+	Hs
		317188 RPA1_HUMAN (912-1446): 2.52e-35: 150: 14.81		RUVB1_HUMAN (10-448): 0: 658: 41.72
+	Hs
		625106 RPB1_HUMAN (1529-1719): 2.52e-19: 97.6: 70.23		RUVB2_HUMAN (4-451): 0: 680: 68.15
+	Mm
		444957 RPB1_MOUSE (1518-1732): 2.59e-14: 81.1: 65.53		RUVB1_MOUSE (10-448): 0: 658: 41.72