HitPredict

Interactor 1: RPC1 (P04051)
DNA-directed RNA polymerase III subunit RPC1 (RNA polymerase III subunit C1) (EC 2.7.7.6) (DNA-directed RNA polymerase III largest subunit) (RNA polymerase III subunit C160)
Gene: RPO31

Interactor 2: RPAB1 (P20434)
DNA-directed RNA polymerases I, II, and III subunit RPABC1 (RNA polymerases I, II, and III subunit ABC1) (ABC27) (DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide)
Gene: RPB5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.960

The method score is based on:

Property Details
Experiments 10393904, 11805826, 17179178, 16429126, 30192228, 37968396, 20967027
Identification Methods two hybrid, tandem affinity purification, affinity chromatography technology, electron microscopy
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rpb1_1~RNA_pol_Rpb5_C, RNA_pol_Rpb1_1~RNA_pol_Rpb5_N, RNA_pol_Rpb1_5~RNA_pol_Rpb5_C, RNA_pol_Rpb1_5~RNA_pol_Rpb5_N
Common GO terms GO:0001056 - RNA polymerase III activity
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005666 - RNA polymerase III complex
and 4 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 1460
Sc

1 215
+ Bt
+ Hs
+ Hs
+ At
+ Sc
+ Sp
+ Hv
+ At
+ At
+ Hs
+ Sc
+ Hv
+ At
+ At

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Last updated: 15 Jul 2024