HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: THOC6 (Q86W42)
THO complex subunit 6 (Functional spliceosome-associated protein 35) (fSAP35) (WD repeat-containing protein 58)
Gene: THOC6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	27684187
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 341
+	Hs
		374829 RASH_HUMAN (1-188): 8.44e-87: 254: 86.77		FBXW7_HUMAN (1-149): 1.68e-20: 94.4: 7.38
+	Hs
		374678 RASH_HUMAN (1-188): 8.44e-87: 254: 86.77		A16L1_HUMAN (65-330): 1.23e-16: 82.9: 15.39
+	Hs
		1144958 RAB35_HUMAN (4-187): 1.26e-82: 244: 31.28		A16L1_HUMAN (65-330): 1.23e-16: 82.9: 15.39
+	Mm
		1244472 RAB35_MOUSE (4-187): 1.26e-82: 244: 31.28		A16L1_MOUSE (13-330): 1.42e-15: 79.4: 16.31
+	Hs
		375612 RASK_HUMAN (16-189): 5.35e-78: 232: 100.00		A16L1_HUMAN (65-330): 1.23e-16: 82.9: 15.39
+	Mm
		746563 RASK_MOUSE (16-189): 2.81e-78: 233: 98.85		A16L1_MOUSE (13-330): 1.42e-15: 79.4: 16.31
+	Hs
		1227433 RAB1B_HUMAN (4-187): 5.49e-74: 223: 32.47		A16L1_HUMAN (65-330): 1.23e-16: 82.9: 15.39
+	Hs
		976335 RB11A_HUMAN (4-184): 5.8e-73: 220: 33.88		A16L1_HUMAN (65-330): 1.23e-16: 82.9: 15.39
+	Hs
		981294 RAB1A_HUMAN (4-187): 3.14e-74: 223: 34.36		FBW10_HUMAN (118-287): 1.64e-15: 79.8: 23.98
+	Hs
		957946 RAB14_HUMAN (4-184): 2.96e-72: 219: 29.51		FBW10_HUMAN (118-287): 1.64e-15: 79.8: 23.98
+	Hs
		964820 RAB1A_HUMAN (4-187): 3.14e-74: 223: 34.36		WDR5_HUMAN (1-103): 2.92e-14: 74.3: 13.76
+	Hs
		965231 RAB1B_HUMAN (4-187): 5.49e-74: 223: 32.47		WDR5_HUMAN (1-103): 2.92e-14: 74.3: 13.76
+	Hs
		957904 RAB14_HUMAN (4-184): 2.96e-72: 219: 29.51		WDR5_HUMAN (1-103): 2.92e-14: 74.3: 13.76
+	Hs
		982067 RAP1A_HUMAN (1-165): 7.87e-63: 194: 58.08		GBB1_HUMAN (117-339): 7.72e-23: 98.9: 12.41
+	Sc
		376225 RAS2_YEAST (3-164): 2.52e-58: 187: 64.42		TAF5_YEAST (160-330): 6.61e-12: 68.5: 9.77