Protein: FBW10
F-box/WD repeat-containing protein 10 (F-box and WD-40 domain-containing protein 10) (Ubiquitin ligase-specificity factor)

Gene: FBW10, FBXW10
Organism: Homo sapiens
Interactions: 136
UniProt ID: Q5XX13

Gene Ontology (top 5):
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

957098

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

18

Small-scale

0.647

High

162600

ANM5
Protein arginine N-methyltransferase 5

1

9

High-throughput

0.618

High

899432

TCPD
T-complex protein 1 subunit delta

1

20

High-throughput

0.618

High

992212

SKP1
S-phase kinase-associated protein 1

1

20

Small-scale

0.618

High

1099700

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

2

High-throughput

0.618

High

1220990

FBW10
F-box/WD repeat-containing protein 10

1

17

High-throughput

0.618

High

1221017

TCPH
T-complex protein 1 subunit eta

1

20

High-throughput

0.618

High

1221018

MEP50
Methylosome protein WDR77

1

19

High-throughput

0.618

High

1221028

MBNL1
Muscleblind-like protein 1

1

2

High-throughput

0.618

High

456755

ANXA2
Annexin A2

1

6

Small-scale

0.561

High

869047

TISD
mRNA decay activator protein ZFP36L2

1

2

High-throughput

0.553

High

979814

H4
Histone H4

1

10

High-throughput

0.553

High

1127725

HLTF
Helicase-like transcription factor

1

11

High-throughput

0.553

High

1220991

H3C
Histone H3.3C

1

15

High-throughput

0.553

High

1220996

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.553

High

1221031

Z3H7B
Zinc finger CCCH domain-containing protein 7B

1

20

High-throughput

0.553

High

1221014

CUL5
Cullin-5

1

20

High-throughput

0.536

High

172929

XPO1
Exportin-1

1

13

High-throughput

0.479

High

209583

SERA
D-3-phosphoglycerate dehydrogenase

1

10

High-throughput

0.479

High

258930

DNJA2
DnaJ homolog subfamily A member 2

1

18

High-throughput

0.479

High

347098

BAG2
BAG family molecular chaperone regulator 2

1

4

High-throughput

0.479

High

358706

LDHA
L-lactate dehydrogenase A chain

1

5

High-throughput

0.479

High

407303

K2C6B
Keratin, type II cytoskeletal 6B

1

7

High-throughput

0.479

High

408926

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

8

High-throughput

0.479

High

428166

RLA1
Large ribosomal subunit protein P1

1

2

High-throughput

0.479

High

428420

RLA2
Large ribosomal subunit protein P2

1

3

High-throughput

0.479

High

452291

PDIA1
Protein disulfide-isomerase

1

10

High-throughput

0.479

High

457102

CAN1
Calpain-1 catalytic subunit

1

2

High-throughput

0.479

High

457495

TBB5
Tubulin beta chain

1

20

High-throughput

0.479

High

468488

HS90B
Heat shock protein HSP 90-beta

1

18

High-throughput

0.479

High

476337

K1C16
Keratin, type I cytoskeletal 16

1

8

High-throughput

0.479

High

528275

THIO
Thioredoxin

1

14

High-throughput

0.479

High

537326

HSP7C
Heat shock cognate 71 kDa protein

1

17

High-throughput

0.479

High

559383

XRCC5
X-ray repair cross-complementing protein 5

1

4

High-throughput

0.479

High

577793

PLAK
Junction plakoglobin

1

20

High-throughput

0.479

High

585796

PHKG2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform

1

5

High-throughput

0.479

High

631660

RAB6A
Ras-related protein Rab-6A

1

6

High-throughput

0.479

High

693791

RL10
Large ribosomal subunit protein uL16

1

6

High-throughput

0.479

High

711710

RABP2
Cellular retinoic acid-binding protein 2

1

2

High-throughput

0.479

High

713797

RBMS1
RNA-binding motif, single-stranded-interacting protein 1

1

13

High-throughput

0.479

High

716886

RL12
Large ribosomal subunit protein uL11

1

4

High-throughput

0.479

High

729309

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

20

High-throughput

0.479

High

761423

HS71L
Heat shock 70 kDa protein 1-like

1

18

High-throughput

0.479

High

785225

RL4
Large ribosomal subunit protein uL4

1

7

High-throughput

0.479

High

807948

SMBP2
DNA-binding protein SMUBP-2

1

10

High-throughput

0.479

High

814816

CUX1
Homeobox protein cut-like 1

1

18

High-throughput

0.479

High

858955

RL27A
Large ribosomal subunit protein uL15

1

11

High-throughput

0.479

High

859865

RL28
Large ribosomal subunit protein eL28

1

3

High-throughput

0.479

High

860237

RS9
Small ribosomal subunit protein uS4

1

8

High-throughput

0.479

High

860790

RS10
Small ribosomal subunit protein eS10

1

9

High-throughput

0.479

High

899967

FXR1
RNA-binding protein FXR1

1

11

High-throughput

0.479

High

912921

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

20

High-throughput

0.479

High

957946

RAB14
Ras-related protein Rab-14

1

5

High-throughput

0.479

High

960141

RL26
Large ribosomal subunit protein uL24

1

6

High-throughput

0.479

High

967462

RS7
Small ribosomal subunit protein eS7

1

6

High-throughput

0.479

High

969264

RS8
Small ribosomal subunit protein eS8

1

6

High-throughput

0.479

High

973208

RS13
Small ribosomal subunit protein uS15

1

5

High-throughput

0.479

High

978995

RS6
Small ribosomal subunit protein eS6

1

6

High-throughput

0.479

High

981294

RAB1A
Ras-related protein Rab-1A

1

5

High-throughput

0.479

High

983838

RBX1
E3 ubiquitin-protein ligase RBX1

1

12

Small-scale

0.479

High

985710

RL11
Large ribosomal subunit protein uL5

1

7

High-throughput

0.479

High

994594

YBOX1
Y-box-binding protein 1

1

6

High-throughput

0.479

High

999654

HBA
Hemoglobin subunit alpha

1

1

High-throughput

0.479

High

1005681

IF4G2
Eukaryotic translation initiation factor 4 gamma 2

1

9

High-throughput

0.479

High

1010856

TMF1
TATA element modulatory factor

1

12

High-throughput

0.479

High

1057177

PRDX1
Peroxiredoxin-1

1

9

High-throughput

0.479

High

1089438

ILF2
Interleukin enhancer-binding factor 2

1

12

High-throughput

0.479

High

1112547

CUL1
Cullin-1

1

20

Small-scale

0.479

High

1132274

GOGB1
Golgin subfamily B member 1

1

20

High-throughput

0.479

High

1152526

ELAV1
ELAV-like protein 1

1

10

High-throughput

0.479

High

1221002

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

1

2

High-throughput

0.479

High

1221005

PUM2
Pumilio homolog 2

1

6

High-throughput

0.479

High

1221008

SCFD1
Sec1 family domain-containing protein 1

1

4

High-throughput

0.479

High

1221010

ATX2L
Ataxin-2-like protein

1

10

High-throughput

0.479

High

1221012

LAR4B
La-related protein 4B

1

8

High-throughput

0.479

High

1221016

GMPPA
Mannose-1-phosphate guanylyltransferase regulatory subunit alpha

1

4

High-throughput

0.479

High

1221023

RBM24
RNA-binding protein 24

1

20

High-throughput

0.479

High

1221029

LATS2
Serine/threonine-protein kinase LATS2

1

12

Small-scale

0.479

High

331877

GOSR1
Golgi SNAP receptor complex member 1

1

0

High-throughput

0.458

High

1025814

BORG5
Cdc42 effector protein 1

1

0

High-throughput

0.458

High

1212739

ZFY27
Protrudin

1

0

High-throughput

0.458

High

1220995

RBPS2
RNA-binding protein with multiple splicing 2

1

0

High-throughput

0.458

High

1221025

FKRP
Ribitol 5-phosphate transferase FKRP

1

0

High-throughput

0.458

High

1221030

IMPA3
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase

1

0

High-throughput

0.458

High

1221034

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.458

High

48003

RBM47
RNA-binding protein 47

1

14

High-throughput

0.437

High

136506

GOLI4
Golgi integral membrane protein 4

1

20

High-throughput

0.437

High

186421

TM9S1
Transmembrane 9 superfamily member 1

1

1

High-throughput

0.437

High

211341

RFOX2
RNA binding protein fox-1 homolog 2

1

14

High-throughput

0.437

High

249249

MA1A2
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB

1

2

High-throughput

0.437

High

387725

FIBA
Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain]

1

4

High-throughput

0.437

High

387846

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

4

High-throughput

0.437

High

387976

FIBG
Fibrinogen gamma chain

1

4

High-throughput

0.437

High

390251

FETA
Alpha-fetoprotein

1

2

High-throughput

0.437

High

576238

PO2F1
POU domain, class 2, transcription factor 1

1

4

High-throughput

0.437

High

587349

SIAT1
Beta-galactoside alpha-2,6-sialyltransferase 1

1

1

High-throughput

0.437

High

620414

NUCL
Nucleolin

1

11

High-throughput

0.437

High

649332

H1T
Histone H1t

1

11

High-throughput

0.437

High

687434

PTBP1
Polypyrimidine tract-binding protein 1

1

20

High-throughput

0.437

High

695688

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.437

High

888891

TMEDA
Transmembrane emp24 domain-containing protein 10

1

2

High-throughput

0.437

High

1083108

GALT2
Polypeptide N-acetylgalactosaminyltransferase 2

1

2

High-throughput

0.437

High

1220992

GOLM2
Protein GOLM2

1

1

High-throughput

0.437

High

1220994

QSOX2
Sulfhydryl oxidase 2

1

14

High-throughput

0.437

High

1220997

ACD11
Acyl-CoA dehydrogenase family member 11

1

1

High-throughput

0.437

High

1220999

NUP54
Nucleoporin p54

1

4

High-throughput

0.437

High

1221000

CCAR1
Cell division cycle and apoptosis regulator protein 1

1

12

High-throughput

0.437

High

1221003

GOLM1
Golgi membrane protein 1

1

1

High-throughput

0.437

High

1221006

GOGA5
Golgin subfamily A member 5

1

20

High-throughput

0.437

High

1221007

TM263
Transmembrane protein 263

1

1

High-throughput

0.437

High

1221011

TM9S4
Transmembrane 9 superfamily member 4

1

1

High-throughput

0.437

High

1221013

GSLG1
Golgi apparatus protein 1

1

1

High-throughput

0.437

High

1221015

C1GLC
C1GALT1-specific chaperone 1

1

1

High-throughput

0.437

High

1221019

TBA1C
Tubulin alpha-1C chain

1

20

High-throughput

0.437

High

1221020

AIF1L
Allograft inflammatory factor 1-like

1

2

High-throughput

0.437

High

1221032

MA1B1
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

1

2

High-throughput

0.437

High

1221033

SIA10
Type 2 lactosamine alpha-2,3-sialyltransferase

1

1

High-throughput

0.437

High

212067

B4GT5
Beta-1,4-galactosyltransferase 5

1

0

High-throughput

0.249

Low

219314

B4GA1
Beta-1,4-glucuronyltransferase 1

1

0

High-throughput

0.249

Low

250936

TPST1
Protein-tyrosine sulfotransferase 1

1

0

High-throughput

0.249

Low

316509

B3GA3
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3

1

0

High-throughput

0.249

Low

687107

MGAT1
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

1

0

High-throughput

0.249

Low

1067015

MGT5A
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A

1

0

High-throughput

0.249

Low

1083065

MGAT2
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

1

0

High-throughput

0.249

Low

1089139

TM115
Transmembrane protein 115

1

0

High-throughput

0.249

Low

1220993

TMCO3
Transmembrane and coiled-coil domain-containing protein 3

1

0

High-throughput

0.249

Low

1220998

HS2ST
Heparan sulfate 2-O-sulfotransferase 1

1

0

High-throughput

0.249

Low

1221001

K2013
Uncharacterized protein KIAA2013

1

0

High-throughput

0.249

Low

1221004

DIK2A
Divergent protein kinase domain 2A

1

0

High-throughput

0.249

Low

1221009

CANT1
Soluble calcium-activated nucleotidase 1

1

0

High-throughput

0.249

Low

1221021

ADPGK
ADP-dependent glucokinase

1

0

High-throughput

0.249

Low

1221022

YIPF4
Protein YIPF4

1

0

High-throughput

0.249

Low

1221024

YIPF3
Protein YIPF3

1

0

High-throughput

0.249

Low

1221026

TM165
Putative divalent cation/proton antiporter TMEM165

1

0

High-throughput

0.249

Low

1221027

XAGE1
X antigen family member 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025