HitPredict

Interactor 1: PABP (P04147)
Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (ARS consensus-binding protein ACBP-67) (Polyadenylate tail-binding protein)
Gene: PAB1

Interactor 2: RNA15 (P25299)
mRNA 3'-end-processing protein RNA15
Gene: RNA15

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	1.00	0.756

Property	Details
Experiments	9199303
Identification Methods	two hybrid, coimmunoprecipitation, biochemical, affinity chromatography technology
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003729 - mRNA binding GO:0006397 - mRNA processing
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 577 Sc			1 296
+	Sc
		376886 PABP_YEAST (1-577): 1.11e-155: 460: 100.00		NOP13_YEAST (10-167): 1.25e-36: 136: 20.63
+	Sc
		376562 PABP_YEAST (1-577): 1.11e-155: 460: 100.00		PABP_YEAST (6-207): 2.72e-29: 118: 11.33
+	Hs
		474021 PAB4L_HUMAN (216-412): 3.83e-40: 151: 26.26		PABP4_HUMAN (19-187): 6.16e-31: 123: 15.88
+	Hs
		680422 TIA1_HUMAN (8-216): 8.71e-40: 151: 21.58		TIA1_HUMAN (13-238): 1.16e-31: 122: 14.72
+	Mm
		665745 TIA1_MOUSE (8-216): 1.06e-40: 153: 21.58		PABP1_MOUSE (19-191): 1.11e-28: 117: 13.56
+	Hs
		680439 TIA1_HUMAN (8-216): 8.71e-40: 151: 21.58		TIAR_HUMAN (11-214): 2.22e-30: 119: 15.79
+	Hs
		1031328 PABP4_HUMAN (3-218): 3.47e-31: 130: 24.79		RBM39_HUMAN (2-101): 5.57e-35: 134: 32.35
+	Hs
		474019 PAB4L_HUMAN (216-412): 3.83e-40: 151: 26.26		ELAV2_HUMAN (11-100): 1.56e-23: 100: 24.44
+	Hs
		516495 PABP4_HUMAN (3-218): 3.47e-31: 130: 24.79		PABP1_HUMAN (19-191): 1.11e-28: 117: 13.56
+	Hs
		516689 PABP3_HUMAN (21-218): 4.94e-30: 126: 25.23		PABP1_HUMAN (19-191): 1.11e-28: 117: 13.56
+	Hs
		582290 NUCL_HUMAN (219-418): 4.27e-23: 105: 20.00		RBM39_HUMAN (2-101): 5.57e-35: 134: 32.35
+	Hs
		1020249 PABP4_HUMAN (3-218): 3.47e-31: 130: 24.79		ELAV2_HUMAN (11-100): 1.56e-23: 100: 24.44
+	Hs
		516355 NUCL_HUMAN (219-418): 4.27e-23: 105: 20.00		PABP1_HUMAN (19-191): 1.11e-28: 117: 13.56
+	Hs
		1119141 PABP5_HUMAN (1-120): 1.45e-16: 83.7: 14.05		PAP1L_HUMAN (19-224): 1.99e-31: 124: 12.21
+	Hs
		516635 PABP5_HUMAN (1-120): 1.45e-16: 83.7: 14.05		PABP1_HUMAN (19-191): 1.11e-28: 117: 13.56
+	Zm
		8143 A0A1D6ELH4_MAIZE (2-225): 6.14e-19: 92.5: 14.29		A0A1D6ELH4_MAIZE (16-189): 3.73e-25: 107: 15.73
+	Hs
		1020306 PABP5_HUMAN (1-120): 1.45e-16: 83.7: 14.05		ELAV2_HUMAN (11-100): 1.56e-23: 100: 24.44
+	Hs
		474034 PABP5_HUMAN (1-120): 1.45e-16: 83.7: 14.05		PAB4L_HUMAN (19-96): 1.19e-22: 97.9: 25.64