Interactor 1: NPY (P01303)
Pro-neuropeptide Y [Cleaved into: Neuropeptide Y (Neuropeptide tyrosine) (NPY); C-flanking peptide of NPY (CPON)]
Gene: NPY

Interactor 2: NPY2R (P49146)
Neuropeptide Y receptor type 2 (NPY2-R) (NPY-Y2 receptor) (Y2 receptor)
Gene: NPY2R

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 23597562
Identification Methods scintillation proximity assay
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_1~Hormone_3
Common GO terms GO:0005246 - calcium channel regulator activity
GO:0010811 - positive regulation of cell-substrate adhesion
GO:0099538 - synaptic signaling via neuropeptide
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 97
Hs

1 381
+ Hs
+ Hs
+ Hs

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Last updated: 11Aug2025