HitPredict

Interactor 1: MYCN (P04198)
N-myc proto-oncogene protein (Class E basic helix-loop-helix protein 37) (bHLHe37)
Gene: MYCN

Interactor 2: UBP5 (P45974)
Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.4.19.12) (Deubiquitinating enzyme 5) (Isopeptidase T) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5)
Gene: USP5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33658627
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 464 Hs			1 858
+	Hs
		346171 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		UBP5_HUMAN (1-858): 0: 842: 100.00
+	Hs
		607792 USF1_HUMAN (184-463): 1.05e-29: 119: 17.83		UBP5_HUMAN (1-858): 0: 842: 100.00
+	Hs
		347510 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		UBP13_HUMAN (2-858): 0: 721: 59.47
+	Hs
		252929 MITF_HUMAN (65-462): 8.44e-27: 114: 13.27		UBP13_HUMAN (2-858): 0: 721: 59.47
+	Hs
		348252 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		UBP22_HUMAN (139-682): 5.21e-111: 352: 14.11
+	Hs
		379972 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		UBP36_HUMAN (250-817): 9.73e-85: 295: 13.61
+	Hs
		379685 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		UBP7_HUMAN (247-777): 7.21e-80: 281: 13.17
+	Hs
		379471 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		UBP39_HUMAN (133-660): 1.38e-83: 280: 14.87
+	Hs
		347922 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		UBP42_HUMAN (264-807): 5.1e-86: 301: 11.96
+	Hs
		347511 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		USP9X_HUMAN (289-758): 2.24e-84: 298: 16.20
+	Hs
		348110 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		UBP36_HUMAN (250-817): 9.73e-85: 295: 13.61
+	Hs
		347512 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		UBP7_HUMAN (247-777): 7.21e-80: 281: 13.17
+	Hs
		346960 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		UBP39_HUMAN (133-660): 1.38e-83: 280: 14.87
+	Hs
		64198 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		UBP27_HUMAN (262-682): 6.68e-84: 277: 14.69
+	Hs
		738985 SRBP1_HUMAN (86-464): 8.15e-36: 143: 14.25		UBP7_HUMAN (247-777): 7.21e-80: 281: 13.17
+	Hs
		347416 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		UBP33_HUMAN (174-457): 8.74e-23: 106: 21.60
+	Hs
		348388 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		UBP3_HUMAN (702-853): 3.54e-15: 81.2: 16.35
+	Hs
		271012 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		UBP2_HUMAN (700-854): 1.43e-11: 70.1: 16.05
+	Dm
		1373210 MYC_DROME (210-462): 2.89e-27: 117: 17.12		UBP36_DROME (326-730): 1.08e-20: 100: 16.04