Protein: ICE2
Little elongation complex subunit 2 (Interactor of little elongator complex ELL subunit 2) (NMDA receptor-regulated protein 2)

Gene: ICE2
Organism: Homo sapiens
Interactions: 64
UniProt ID: Q659A1

Gene Ontology (top 5):
GO:0000791 - euchromatin
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0008023 - transcription elongation factor complex
GO:0015030 - Cajal body

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1226006

ELL3
RNA polymerase II elongation factor ELL3

5

2

Small-scale

0.709

High

1225999

EAF1
ELL-associated factor 1

4

0

High-throughput

0.670

High

485655

RU2A
U2 small nuclear ribonucleoprotein A'

4

0

High-throughput

0.661

High

425730

PERM
Myeloperoxidase

3

0

High-throughput

0.638

High

469798

CATG
Cathepsin G

3

0

High-throughput

0.638

High

936599

ELL
RNA polymerase II elongation factor ELL

2

2

Small-scale

0.628

High

471861

RU2B
U2 small nuclear ribonucleoprotein B''

2

1

High-throughput

0.601

High

1226011

ICE1
Little elongation complex subunit 1

2

0

Small-scale

0.585

High

1194145

LARP7
La-related protein 7

1

1

High-throughput

0.536

High

1225994

LAR4B
La-related protein 4B

1

1

High-throughput

0.536

High

1226003

SIKE1
Suppressor of IKBKE 1

1

1

High-throughput

0.536

High

1226009

FGOP2
FGFR1 oncogene partner 2

1

1

High-throughput

0.536

High

1226013

DYR1B
Dual specificity tyrosine-phosphorylation-regulated kinase 1B

1

1

High-throughput

0.536

High

250655

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

0

High-throughput

0.513

High

280662

PR40A
Pre-mRNA-processing factor 40 homolog A

1

0

High-throughput

0.513

High

290035

OFD1
Centriole and centriolar satellite protein OFD1

1

0

High-throughput

0.513

High

336001

MED26
Mediator of RNA polymerase II transcription subunit 26

1

0

High-throughput

0.513

High

549611

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

0

High-throughput

0.513

High

593131

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

High-throughput

0.513

High

884649

SYHM
Histidine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

959345

RAP1B
Ras-related protein Rap-1b

1

0

High-throughput

0.513

High

1154645

VAMP3
Vesicle-associated membrane protein 3

1

0

High-throughput

0.513

High

1225995

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

0

High-throughput

0.513

High

1226000

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

0

High-throughput

0.513

High

1226001

INT14
Integrator complex subunit 14

1

0

High-throughput

0.513

High

1226002

SORT
Sortilin

1

0

High-throughput

0.513

High

1226004

RBM42
RNA-binding protein 42

1

0

High-throughput

0.513

High

1226005

DSN1
Kinetochore-associated protein DSN1 homolog

1

0

High-throughput

0.513

High

1226012

RRP44
Exosome complex exonuclease RRP44

1

0

High-throughput

0.513

High

379657

IGHA1
Immunoglobulin heavy constant alpha 1

2

2

High-throughput

0.504

High

1115726

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

1

High-throughput

0.479

High

138166

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

0

High-throughput

0.458

High

315685

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

345940

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

628804

TBP
TATA-box-binding protein

1

0

High-throughput

0.458

High

695692

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

714191

PML
Protein PML

1

0

High-throughput

0.458

High

911616

NCBP2
Nuclear cap-binding protein subunit 2

1

0

High-throughput

0.458

High

977726

ACTA
Actin, aortic smooth muscle

1

0

High-throughput

0.458

High

989004

AP2B1
AP-2 complex subunit beta

1

0

High-throughput

0.458

High

1225993

TCPW
T-complex protein 1 subunit zeta-2

1

0

High-throughput

0.458

High

137332

ELL2
RNA polymerase II elongation factor ELL2

1

2

Small-scale

0.445

High

574316

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

0

High-throughput

0.426

High

379106

IGKC
Immunoglobulin kappa constant

1

1

High-throughput

0.407

High

379362

IGHG2
Immunoglobulin heavy constant gamma 2

1

2

High-throughput

0.407

High

366181

HPT
Haptoglobin

3

0

High-throughput

0.347

High

369354

A1AT
Alpha-1-antitrypsin

3

0

High-throughput

0.347

High

378999

PIGR
Polymeric immunoglobulin receptor

3

0

High-throughput

0.347

High

391031

TRFL
Lactotransferrin

3

0

High-throughput

0.347

High

1226007

MUC5B
Mucin-5B

3

0

High-throughput

0.347

High

1226008

BPIA1
BPI fold-containing family A member 1

3

0

High-throughput

0.347

High

1226010

DMBT1
Scavenger receptor cysteine-rich domain-containing protein DMBT1

3

0

High-throughput

0.347

High

378692

IGJ
Immunoglobulin J chain

2

0

High-throughput

0.328

High

189631

STX7
Syntaxin-7

1

0

High-throughput

0.279

Low

239093

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.279

Low

329285

LETM1
Mitochondrial proton/calcium exchanger protein

1

0

High-throughput

0.279

Low

463984

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

0

High-throughput

0.279

Low

903563

IDH3G
Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial

1

0

High-throughput

0.279

Low

1225998

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.279

Low

642929

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

0

High-throughput

0.249

Low

1225992

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1225996

VP33A
Vacuolar protein sorting-associated protein 33A

1

0

High-throughput

0.249

Low

1225997

PAUF
Pancreatic adenocarcinoma up-regulated factor

1

0

High-throughput

0.249

Low

58835

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025