Protein: IGHG2
Immunoglobulin heavy constant gamma 2 (Ig gamma-2 chain C region) (Ig gamma-2 chain C region DOT) (Ig gamma-2 chain C region TIL) (Ig gamma-2 chain C region ZIE)

Gene: IGHG2
Organism: Homo sapiens
Interactions: 103
UniProt ID: P01859

Gene Ontology (top 5):
GO:0002250 - adaptive immune response
GO:0003823 - antigen binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

132965

MATN2
Matrilin-2

1

11

High-throughput

0.575

High

210648

KLK10
Kallikrein-10

1

11

High-throughput

0.575

High

379173

IGHG1
Immunoglobulin heavy constant gamma 1

1

17

High-throughput

0.575

High

379326

IGHG3
Immunoglobulin heavy constant gamma 3

1

17

High-throughput

0.575

High

379327

ALBU
Albumin

1

6

High-throughput

0.575

High

379328

HV431
Immunoglobulin heavy variable 4-31

1

17

High-throughput

0.575

High

379348

ANK2
Ankyrin-2

1

4

High-throughput

0.575

High

379358

FNDC1
Fibronectin type III domain-containing protein 1

1

16

High-throughput

0.575

High

379376

FNDC5
Fibronectin type III domain-containing protein 5

1

6

High-throughput

0.575

High

379338

1433T
14-3-3 protein theta

2

7

High-throughput

0.552

High

379384

SUSD3
Sushi domain-containing protein 3

2

2

High-throughput

0.552

High

379341

CAH8
Carbonic anhydrase-related protein

1

5

High-throughput

0.514

High

379374

GDPD1
Lysophospholipase D GDPD1

2

2

High-throughput

0.504

High

379375

ASCC1
Activating signal cointegrator 1 complex subunit 1

2

4

High-throughput

0.504

High

379385

SNX27
Sorting nexin-27

2

11

High-throughput

0.504

High

379386

CDK15
Cyclin-dependent kinase 15

2

5

High-throughput

0.504

High

379396

DDX31
ATP-dependent DNA helicase DDX31

2

10

High-throughput

0.504

High

379332

AK1A1
Aldo-keto reductase family 1 member A1

1

0

High-throughput

0.458

High

132550

UPK1A
Uroplakin-1a

1

12

High-throughput

0.445

High

194438

P2RX6
P2X purinoceptor 6

1

4

High-throughput

0.445

High

254716

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

9

High-throughput

0.445

High

351631

SG1D1
Secretoglobin family 1D member 1

1

6

High-throughput

0.445

High

379329

TAU
Microtubule-associated protein tau

1

3

High-throughput

0.445

High

379330

BIP
Endoplasmic reticulum chaperone BiP

1

14

High-throughput

0.445

High

379334

AATC
Aspartate aminotransferase, cytoplasmic

1

7

High-throughput

0.445

High

379339

AL3A1
Aldehyde dehydrogenase, dimeric NADP-preferring

1

11

High-throughput

0.445

High

379340

CCR1
C-C chemokine receptor type 1

1

16

High-throughput

0.445

High

379343

STX17
Syntaxin-17

1

4

High-throughput

0.445

High

379345

TCPB
T-complex protein 1 subunit beta

1

1

High-throughput

0.445

High

379351

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

7

High-throughput

0.445

High

379370

SULF2
Extracellular sulfatase Sulf-2

1

3

High-throughput

0.445

High

379378

ITLN2
Intelectin-2

1

6

High-throughput

0.445

High

379380

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

5

High-throughput

0.445

High

379387

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

1

High-throughput

0.445

High

379389

EGFL8
Epidermal growth factor-like protein 8

1

15

High-throughput

0.445

High

379394

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

6

High-throughput

0.445

High

379409

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

8

High-throughput

0.445

High

379410

DD19B
ATP-dependent RNA helicase DDX19B

1

6

High-throughput

0.445

High

277231

PITX3
Pituitary homeobox 3

1

4

Small-scale

0.437

High

379353

USF2
Upstream stimulatory factor 2

1

6

High-throughput

0.437

High

340602

STABP
STAM-binding protein

1

0

High-throughput

0.426

High

379403

PLS4
Phospholipid scramblase 4

1

0

High-throughput

0.426

High

379406

DKK2
Dickkopf-related protein 2

1

0

High-throughput

0.426

High

231365

PDE6D
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta

1

2

High-throughput

0.407

High

251335

CIDEA
Lipid transferase CIDEA

1

1

High-throughput

0.407

High

325254

OR2A4
Olfactory receptor 2A4

1

7

High-throughput

0.407

High

327140

ZFPL1
Zinc finger protein-like 1

1

2

High-throughput

0.407

High

379331

ADT3
ADP/ATP translocase 3

1

6

High-throughput

0.407

High

379333

ZSC20
Zinc finger and SCAN domain-containing protein 20

1

2

High-throughput

0.407

High

379335

ATF6A
Cyclic AMP-dependent transcription factor ATF-6 alpha

1

2

High-throughput

0.407

High

379336

CCNA2
Cyclin-A2

1

2

High-throughput

0.407

High

379337

CP3A5
Cytochrome P450 3A5

1

1

High-throughput

0.407

High

379342

PTSS1
Phosphatidylserine synthase 1

1

4

High-throughput

0.407

High

379344

DSCR6
Protein ripply3

1

3

High-throughput

0.407

High

379346

SSBP2
Single-stranded DNA-binding protein 2

1

6

High-throughput

0.407

High

379347

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

8

High-throughput

0.407

High

379349

STK4
Serine/threonine-protein kinase 4

1

12

High-throughput

0.407

High

379350

STK3
Serine/threonine-protein kinase 3

1

10

High-throughput

0.407

High

379352

ABRX2
BRISC complex subunit Abraxas 2

1

1

High-throughput

0.407

High

379354

MK06
Mitogen-activated protein kinase 6

1

2

High-throughput

0.407

High

379355

KAT1
Kynurenine--oxoglutarate transaminase 1

1

10

High-throughput

0.407

High

379356

UPP1
Uridine phosphorylase 1

1

3

High-throughput

0.407

High

379357

CR021
UPF0711 protein C18orf21

1

7

High-throughput

0.407

High

379359

EMC4
ER membrane protein complex subunit 4

1

3

High-throughput

0.407

High

379360

MYOME
Myomegalin

1

6

High-throughput

0.407

High

379361

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

9

High-throughput

0.407

High

379362

ICE2
Little elongation complex subunit 2

1

2

High-throughput

0.407

High

379363

SFXN4
Sideroflexin-4

1

6

High-throughput

0.407

High

379364

MCAF1
Activating transcription factor 7-interacting protein 1

1

2

High-throughput

0.407

High

379365

KHDC4
KH homology domain-containing protein 4

1

1

High-throughput

0.407

High

379366

MTA70
N(6)-adenosine-methyltransferase catalytic subunit METTL3

1

3

High-throughput

0.407

High

379367

CIR1
Corepressor interacting with RBPJ 1

1

7

High-throughput

0.407

High

379368

Z354C
Zinc finger protein 354C

1

1

High-throughput

0.407

High

379369

CERS3
Ceramide synthase 3

1

6

High-throughput

0.407

High

379371

NRSN1
Neurensin-1

1

6

High-throughput

0.407

High

379372

ARM10
Armadillo repeat-containing protein 10

1

1

High-throughput

0.407

High

379373

FRMD1
FERM domain-containing protein 1

1

6

High-throughput

0.407

High

379377

RHBL4
Rhomboid-related protein 4

1

8

High-throughput

0.407

High

379379

PIGT
GPI-anchor transamidase component PIGT

1

6

High-throughput

0.407

High

379382

SARAF
Store-operated calcium entry-associated regulatory factor

1

4

High-throughput

0.407

High

379383

SMIM8
Small integral membrane protein 8

1

1

High-throughput

0.407

High

379388

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

11

High-throughput

0.407

High

379390

FUND2
FUN14 domain-containing protein 2

1

2

High-throughput

0.407

High

379391

RBM24
RNA-binding protein 24

1

6

High-throughput

0.407

High

379392

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

9

High-throughput

0.407

High

379393

SRRT
Serrate RNA effector molecule homolog

1

2

High-throughput

0.407

High

379395

SAV1
Protein salvador homolog 1

1

5

High-throughput

0.407

High

379397

COE2
Transcription factor COE2

1

6

High-throughput

0.407

High

379398

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

1

3

High-throughput

0.407

High

379402

MBNL1
Muscleblind-like protein 1

1

4

High-throughput

0.407

High

379404

TB22B
TBC1 domain family member 22B

1

3

High-throughput

0.407

High

379407

MO4L1
Mortality factor 4-like protein 1

1

2

High-throughput

0.407

High

379408

PHF11
PHD finger protein 11

1

12

High-throughput

0.407

High

379411

SSUH2
Protein SSUH2 homolog

1

4

High-throughput

0.407

High

379412

AR2BP
ADP-ribosylation factor-like protein 2-binding protein

1

2

High-throughput

0.407

High

379414

RN115
E3 ubiquitin-protein ligase RNF115

1

8

High-throughput

0.407

High

87293

OSCRI
SCRIB overlapping open reading frame protein

1

0

High-throughput

0.232

Low

379381

ACD
Adrenocortical dysplasia protein homolog

1

0

High-throughput

0.232

Low

379399

MSL2
E3 ubiquitin-protein ligase MSL2

1

0

High-throughput

0.232

Low

379400

GPN1
GPN-loop GTPase 1

1

0

High-throughput

0.232

Low

379401

TIGAR
Fructose-2,6-bisphosphatase TIGAR

1

0

High-throughput

0.232

Low

379405

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

0

High-throughput

0.232

Low

379413

FCF1
rRNA-processing protein FCF1 homolog

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025