HitPredict

Interactor 1: K2C6B (P04259)
Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK-6B) (Keratin-6B) (K6B) (Type-II keratin Kb10)
Gene: KRT6B

Interactor 2: UBS3B (Q8TF42)
Ubiquitin-associated and SH3 domain-containing protein B (EC 3.1.3.48) (Cbl-interacting protein p70) (Suppressor of T-cell receptor signaling 1) (STS-1) (T-cell ubiquitin ligand 2) (TULA-2) (Tyrosine-protein phosphatase STS1/TULA2)
Gene: UBASH3B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 564 Hs			1 649
+	Hs
		729142 K22E_HUMAN (135-521): 1.87e-166: 489: 68.48		UBS3B_HUMAN (1-649): 0: 1066: 100.00
+	Hs
		380655 K2C1_HUMAN (128-494): 1.13e-164: 484: 73.84		UBS3B_HUMAN (1-649): 0: 1066: 100.00
+	Hs
		409176 K2C8_HUMAN (135-511): 8.34e-165: 479: 68.44		UBS3B_HUMAN (1-649): 0: 1066: 100.00
+	Hs
		1205248 K2C73_HUMAN (3-560): 4.87e-98: 309: 53.94		UBS3B_HUMAN (1-649): 0: 1066: 100.00
+	Hs
		359518 K2C6A_HUMAN (1-499): 4.38e-86: 279: 98.60		UBS3B_HUMAN (1-649): 0: 1066: 100.00
+	Hs
		531608 K2C5_HUMAN (3-479): 4.55e-85: 277: 76.61		UBS3B_HUMAN (1-649): 0: 1066: 100.00
+	Hs
		883376 KRT35_HUMAN (47-522): 8.57e-82: 265: 22.90		UBS3A_HUMAN (12-643): 0: 947: 43.37
+	Hs
		729063 K22E_HUMAN (135-521): 1.87e-166: 489: 68.48		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		380590 K2C1_HUMAN (128-494): 1.13e-164: 484: 73.84		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		409046 K2C8_HUMAN (135-511): 8.34e-165: 479: 68.44		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		444533 K2C7_HUMAN (103-535): 4.36e-157: 459: 63.39		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		729089 K22E_HUMAN (135-521): 1.87e-166: 489: 68.48		LASP1_HUMAN (254-315): 1.29e-12: 70.2: 30.65
+	Hs
		924679 K2C73_HUMAN (3-560): 4.87e-98: 309: 53.94		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		924576 KRT81_HUMAN (47-560): 2.27e-91: 291: 46.72		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		924470 KRT85_HUMAN (1-535): 4.88e-90: 288: 47.48		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		924469 KRT83_HUMAN (41-548): 1.04e-89: 286: 47.05		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		213936 KRT86_HUMAN (47-542): 1.4e-88: 283: 47.58		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		359480 K2C6A_HUMAN (1-499): 4.38e-86: 279: 98.60		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		531551 K2C5_HUMAN (3-479): 4.55e-85: 277: 76.61		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		924741 KRT35_HUMAN (47-522): 8.57e-82: 265: 22.90		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56